ApreciseKUre: an approach of Precision Medicine in a Rare Disease

Por Spiga, Ottavia, Cicaloni, Vittoria, Bernini, Andrea, Zatkova, Andrea, Santucci, Annalisa
Publicado no BMC Med Inform Decis Mak (2017)

A possible strategy to fight COVID-19: Interfering with spike glycoprotein trimerization

Por Bongini, Pietro, Trezza, Alfonso, Bianchini, Monica, Spiga, Ottavia, Niccolai, Neri
Publicado no Biochem Biophys Res Commun (2020)

An integrated drug repurposing strategy for the rapid identification of potential SARS-CoV-2 viral inhibitors

Por Trezza, Alfonso, Iovinelli, Daniele, Santucci, Annalisa, Prischi, Filippo, Spiga, Ottavia
Publicado no Sci Rep (2020)

From in silico to in vitro: a trip to reveal flavonoid binding on the Rattus norvegicus Kir6.1 ATP-sensitive inward rectifier potassium channel

Por Trezza, Alfonso, Cicaloni, Vittoria, Porciatti, Piera, Langella, Andrea, Fusi, Fabio, Saponara, Simona, Spiga, Ottavia
Publicado no PeerJ (2018)

Structural investigation of Rett-inducing MeCP2 mutations()

Por Spiga, Ottavia, Gardini, Simone, Rossi, Nicole, Cicaloni, Vittoria, Pettini, Francesco, Niccolai, Neri, Santucci, Annalisa
Publicado no Genes Dis (2018)

Hydration studies on the archaeal protein Sso7d using NMR measurements and MD simulations

Por Bernini, Andrea, Spiga, Ottavia, Consonni, Roberto, Arosio, Ivana, Fusi, Paola, Cirri, Simone, Guagliardi, Annamaria, Niccolai, Neri
Publicado em 2011

The Selective Rat Toxicant Norbormide Blocks K(ATP) Channels in Smooth Muscle Cells But Not in Insulin-Secreting Cells

Por Saponara, Simona, Fusi, Fabio, Spiga, Ottavia, Trezza, Alfonso, Hopkins, Brian, Brimble, Margaret A., Rennison, David, Bova, Sergio
Publicado no Front Pharmacol (2019)

Tertiary structure prediction of SARS coronavirus helicase

Por Bernini, Andrea, Spiga, Ottavia, Venditti, Vincenzo, Prischi, Filippo, Bracci, Luisa, Huang, Jiandong, Tanner, Julian A., Niccolai, Neri
Publicado no Biochem Biophys Res Commun (2006)

Molecular modelling of S1 and S2 subunits of SARS coronavirus spike glycoprotein

Por Spiga, Ottavia, Bernini, Andrea, Ciutti, Arianna, Chiellini, Stefano, Menciassi, Nicola, Finetti, Francesca, Causarono, Vincenza, Anselmi, Francesca, Prischi, Filippo, Niccolai, Neri
Publicado no Biochem Biophys Res Commun (2003)

Interactive alkaptonuria database: investigating clinical data to improve patient care in a rare disease

Por Cicaloni, Vittoria, Spiga, Ottavia, Dimitri, Giovanna Maria, Maiocchi, Rebecca, Millucci, Lia, Giustarini, Daniela, Bernardini, Giulia, Bernini, Andrea, Marzocchi, Barbara, Braconi, Daniela, Santucci, Annalisa
Publicado no FASEB J (2019)

Probing the surface of a sweet protein: NMR study of MNEI with a paramagnetic probe

Por Niccolai, Neri, Spadaccini, Roberta, Scarselli, Maria, Bernini, Andrea, Crescenzi, Orlando, Spiga, Ottavia, Ciutti, Arianna, Di Maro, Daniela, Bracci, Luisa, Dalvit, Claudio, Temussi, Piero A.
Publicado em 2001

Machine learning application for development of a data-driven predictive model able to investigate quality of life scores in a rare disease

Por Spiga, Ottavia, Cicaloni, Vittoria, Fiorini, Cosimo, Trezza, Alfonso, Visibelli, Anna, Millucci, Lia, Bernardini, Giulia, Bernini, Andrea, Marzocchi, Barbara, Braconi, Daniela, Prischi, Filippo, Santucci, Annalisa
Publicado no Orphanet J Rare Dis (2020)

Omic Approach in Non-smoker Female with Lung Squamous Cell Carcinoma Pinpoints to Germline Susceptibility and Personalized Medicine

Por Baldassarri, Margherita, Fallerini, Chiara, Cetta, Francesco, Ghisalberti, Marco, Bellan, Cristiana, Furini, Simone, Spiga, Ottavia, Crispino, Sergio, Gotti, Giuseppe, Ariani, Francesca, Paladini, Piero, Renieri, Alessandra, Frullanti, Elisa
Publicado no Cancer Res Treat (2018)

On the mechanisms of bananin activity against severe acute respiratory syndrome coronavirus

Por Wang, Zai, Huang, Jian‐Dong, Wong, Kin‐Ling, Wang, Pei‐Gang, Zhang, Hao‐Jie, Tanner, Julian A., Spiga, Ottavia, Bernini, Andrea, Zheng, Bo‐Jian, Niccolai, Neri
Publicado no FEBS J (2011)

MECP2 missense mutations outside the canonical MBD and TRD domains in males with intellectual disability

Por Bianciardi, Laura, Fichera, Marco, Failla, Pinella, Di Marco, Chiara, Grozeva, Detelina, Mencarelli, Maria Antonietta, Spiga, Ottavia, Mari, Francesca, Meloni, Ilaria, Raymond, Lucy, Renieri, Alessandra, Romano, Corrado, Ariani, Francesca
Publicado no J Hum Genet (2015)

Prediction of quaternary assembly of SARS coronavirus peplomer

Por Bernini, Andrea, Spiga, Ottavia, Ciutti, Arianna, Chiellini, Stefano, Bracci, Luisa, Yan, Xiyun, Zheng, Bojian, Huang, Jiandong, He, Ming-Liang, Song, Huai-Dong, Hao, Pei, Zhao, Guoping, Niccolai, Neri
Publicado no Biochem Biophys Res Commun (2004)

Homogentisate 1,2-dioxygenase (HGD) gene variants, their analysis and genotype–phenotype correlations in the largest cohort of patients with AKU

Por Ascher, David B., Spiga, Ottavia, Sekelska, Martina, Pires, Douglas E. V., Bernini, Andrea, Tiezzi, Monica, Kralovicova, Jana, Borovska, Ivana, Soltysova, Andrea, Olsson, Birgitta, Galderisi, Silvia, Cicaloni, Vittoria, Ranganath, Lakshminarayan, Santucci, Annalisa, Zatkova, Andrea
Publicado no Eur J Hum Genet (2019)

FOXG1 Is Responsible for the Congenital Variant of Rett Syndrome

Por Ariani, Francesca, Hayek, Giuseppe, Rondinella, Dalila, Artuso, Rosangela, Mencarelli, Maria Antonietta, Spanhol-Rosseto, Ariele, Pollazzon, Marzia, Buoni, Sabrina, Spiga, Ottavia, Ricciardi, Sara, Meloni, Ilaria, Longo, Ilaria, Mari, Francesca, Broccoli, Vania, Zappella, Michele, Renieri, Alessandra
Publicado em 2008

Revealing the Complexity of a Monogenic Disease: Rett Syndrome Exome Sequencing

Por Grillo, Elisa, Lo Rizzo, Caterina, Bianciardi, Laura, Bizzarri, Veronica, Baldassarri, Margherita, Spiga, Ottavia, Furini, Simone, De Felice, Claudio, Signorini, Cinzia, Leoncini, Silvia, Pecorelli, Alessandra, Ciccoli, Lucia, Mencarelli, Maria Antonietta, Hayek, Joussef, Meloni, Ilaria, Ariani, Francesca, Mari, Francesca, Renieri, Alessandra
Publicado em 2013

Mycobacterium tuberculosis Chaperonin 10 Is Secreted in the Macrophage Phagosome: Is Secretion Due to Dissociation and Adoption of a Partially Helical Structure at the Membrane?

Por Fossati, Gianluca, Izzo, Gaetano, Rizzi, Emanuele, Gancia, Emanuela, Modena, Daniela, Moras, Maria Luisa, Niccolai, Neri, Giannozzi, Elena, Spiga, Ottavia, Bono, Letizia, Marone, Piero, Leone, Eugenio, Mangili, Francesca, Harding, Stephen, Errington, Neil, Walters, Christopher, Henderson, Brian, Roberts, Michael M., Coates, Anthony R. M., Casetta, Bruno, Mascagni, Paolo
Publicado em 2003