Mycobacterium tuberculosis Chaperonin 10 Is Secreted in the Macrophage Phagosome: Is Secretion Due to Dissociation and Adoption of a Partially Helical Structure at the Membrane?

To confirm that Mycobacterium tuberculosis chaperonin 10 (Cpn10) is secreted outside the live bacillus, infected macrophages were examined by electron microscopy. This revealed that the mycobacterial protein accumulates both in the wall of the bacterium and in the matrix of the phagosomes in which i...

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Detalhes bibliográficos
Main Authors: Fossati, Gianluca, Izzo, Gaetano, Rizzi, Emanuele, Gancia, Emanuela, Modena, Daniela, Moras, Maria Luisa, Niccolai, Neri, Giannozzi, Elena, Spiga, Ottavia, Bono, Letizia, Marone, Piero, Leone, Eugenio, Mangili, Francesca, Harding, Stephen, Errington, Neil, Walters, Christopher, Henderson, Brian, Roberts, Michael M., Coates, Anthony R. M., Casetta, Bruno, Mascagni, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164881/
https://ncbi.nlm.nih.gov/pubmed/12837802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.14.4256-4267.2003
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