Preclinical Mouse Models for Analysis of the Therapeutic Potential of Engineered Oncolytic Herpes Viruses

Por Speranza, Maria-Carmela, Kasai, Kazue, Lawler, Sean E.
Publicado no ILAR J (2016)

IMPS-21 EFFECT OF rQNestin 34.5 ONCOLYTIC HERPES VIRUS ON IMMUNE CHECKPOINT GENE EXPRESSION IN GLIOBLASTOMA CELLS AND EVALUATION OF THERAPEUTIC EFFICACY

Por Speranza, Maria-Carmela, Kasai, Kazue, Kaufmann, Johanna, Nakashima, Hiroshi, Lawler, Sean, Chiocca, E. Antonio
Publicado no Neuro Oncol (2015)

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma

Por Speranza, Maria Carmela, Frattini, Véronique, Pisati, Federica, Kapetis, Dimos, Porrati, Paola, Eoli, Marica, Pellegatta, Serena, Finocchiaro, Gaetano
Publicado em 2012

BKM-120 (Buparlisib): A Phosphatidyl-Inositol-3 Kinase Inhibitor with Anti-Invasive Properties in Glioblastoma

Por Speranza, Maria-Carmela, Nowicki, Michal O., Behera, Prajna, Cho, Choi-Fong, Chiocca, E. Antonio, Lawler, Sean E.
Publicado no Sci Rep (2016)

IMMU-28. DEFINING MOLECULAR MECHANISMS OF RESISTANCE TO GLIOBLASTOMA (GBM) IMMUNITY USING A NOVEL CRISPR/CAS9 IN VIVO LOSS-OF-FUNCTION SCREENING PLATFORM

Por Neagu, Martha R, Speranza, Maria Carmela, Manguso, Robert T, Lawler, Sean E, Freeman, Gordon J, Doench, John, Sharpe, Arlene H, Haining, W Nicholas
Publicado no Neuro Oncol (2017)

A Radial Glia Gene Marker, Fatty Acid Binding Protein 7 (FABP7), Is Involved in Proliferation and Invasion of Glioblastoma Cells

Por De Rosa, Antonella, Pellegatta, Serena, Rossi, Marco, Tunici, Patrizia, Magnoni, Letizia, Speranza, Maria Carmela, Malusa, Federico, Miragliotta, Vincenzo, Mori, Elisa, Finocchiaro, Gaetano, Bakker, Annette
Publicado em 2012

FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration

Por Frattini, Véronique, Pisati, Federica, Speranza, Maria Carmela, Poliani, Pietro Luigi, Frigé, Gianmaria, Cantini, Gabriele, Kapetis, Dimos, Cominelli, Manuela, Rossi, Alessandra, Finocchiaro, Gaetano, Pellegatta, Serena
Publicado em 2012

IMMU-15. PD-1 BLOCKADE ACTIVATES CD4 T CELLS AND THE INNATE IMMUNE RESPONSE FOR GLIOBLASTOMA ERADICATION

Por Klein, Sarah R, Speranza, Maria Carmela, Gokhale, Prafulla C, Wilkens, Margaret K, Jones, Kristen L, Kirschmeier, Paul T, Chaudhri, Apoorvi, Reardon, David, Freeman, Gordon J
Publicado no Neuro Oncol (2017)

IMMU-10. EXPRESSION OF PD-L2, IN GLIOBLASTOMA; IMPLICATIONS AS A BIOMARKER FOR IMMUNOTHERAPY

Por Ricklefs, Franz, Hayes, Josie, Speranza, Maria Carmela, Krenzlin, Harald, Costello, Joseph, Freeman, Gordon J, Westphal, Manfred, Lamszus, Katrin, Chiocca, E Antonio, Lawler, Sean E
Publicado no Neuro Oncol (2017)

Design of a Microfluidic Chip for Magnetic-Activated Sorting of One-Bead-One-Compound Libraries

Por Cho, Choi-Fong, Lee, Kyungheon, Speranza, Maria-Carmela, Bononi, Fernanda C., Viapiano, Mariano S., Luyt, Leonard G., Weissleder, Ralph, Chiocca, E. Antonio, Lee, Hakho, Lawler, Sean E.
Publicado no ACS Comb Sci (2016)

Histone Deacetylase Inhibitors Increase p27(Kip1) by Affecting Its Ubiquitin-Dependent Degradation through Skp2 Downregulation

Por Borriello, Adriana, Naviglio, Silvio, Bencivenga, Debora, Caldarelli, Ilaria, Tramontano, Annunziata, Speranza, Maria Carmela, Stampone, Emanuela, Sapio, Luigi, Negri, Aide, Oliva, Adriana, Sinisi, Antonio Agostino, Spina, Annamaria, Della Ragione, Fulvio
Publicado no Oxid Med Cell Longev (2016)

Histone deacetylase 6 inhibition enhances oncolytic viral replication in glioma

Por Nakashima, Hiroshi, Kaufmann, Johanna K., Wang, Pin-Yi, Nguyen, Tran, Speranza, Maria-Carmela, Kasai, Kazue, Okemoto, Kazuo, Otsuki, Akihiro, Nakano, Ichiro, Fernandez, Soledad, Goins, William F., Grandi, Paola, Glorioso, Joseph C., Lawler, Sean, Cripe, Timothy P., Chiocca, E. Antonio
Publicado no J Clin Invest (2015)

Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma

Por Speranza, Maria-Carmela, Passaro, Carmela, Ricklefs, Franz, Kasai, Kazue, Klein, Sarah R, Nakashima, Hiroshi, Kaufmann, Johanna K, Ahmed, Abdul-Kareem, Nowicki, Michal O, Obi, Prisca, Bronisz, Agnieszka, Aguilar-Cordova, Estuardo, Aguilar, Laura K, Guzik, Brian W, Breakefield, Xandra, Weissleder, Ralph, Freeman, Gordon J, Reardon, David A, Wen, Patrick Y, Chiocca, E Antonio, Lawler, Sean E
Publicado no Neuro Oncol (2018)