The IκB-protein BCL-3 controls Toll-like receptor-induced MAPK activity by promoting TPL-2 degradation in the nucleus

per Collins, Patricia E., Somma, Domenico, Kerrigan, David, Herrington, Felicity, Keeshan, Karen, Nibbs, Robert J. B., Carmody, Ruaidhrí J.
Publicat a Proc Natl Acad Sci U S A (2019)

CIKS/DDX3X interaction controls the stability of the Zc3h12a mRNA induced by IL-17

per Somma, Domenico, Mastrovito, Paola, Grieco, Marianeve, Lavorgna, Alfonso, Pignalosa, Angelica, Formisano, Luigi, Salzano, Anna Maria, Scaloni, Andrea, Pacifico, Francesco, Siebenlist, Ulrich, Leonardi, Antonio
Publicat a J Immunol (2015)

The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80

per Smith, Emma L, Somma, Domenico, Kerrigan, David, McIntyre, Zoe, Cole, John J, Liang, Kai Ling, Kiely, Patrick A, Keeshan, Karen, Carmody, Ruaidhrí J
Publicat a Nucleic Acids Res (2019)

The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits

per Mitxitorena, Izaskun, Somma, Domenico, Mitchell, Jennifer P., Lepistö, Matti, Tyrchan, Christian, Smith, Emma L., Kiely, Patrick A., Walden, Helen, Keeshan, Karen, Carmody, Ruaidhrí J.
Publicat a J Biol Chem (2020)

Sphingosine Kinases promote IL-17 expression in human T lymphocytes

per Barra, Giusi, Lepore, Alessio, Gagliardi, Miriam, Somma, Domenico, Matarazzo, Maria Rosaria, Costabile, Francesca, Pasquale, Giuseppe, Mazzoni, Alessio, Gallo, Carmela, Nuzzo, Genoveffa, Annunziato, Francesco, Fontana, Angelo, Leonardi, Antonio, De Palma, Raffaele
Publicat a Sci Rep (2018)

COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1(+) neutrophils and CD14(+) monocytes

per MacDonald, Lucy, Alivernini, Stefano, Tolusso, Barbara, Elmesmari, Aziza, Somma, Domenico, Perniola, Simone, Paglionico, Annamaria, Petricca, Luca, Bosello, Silvia L., Carfì, Angelo, Sali, Michela, Stigliano, Egidio, Cingolani, Antonella, Murri, Rita, Arena, Vincenzo, Fantoni, Massimo, Antonelli, Massimo, Landi, Francesco, Franceschi, Francesco, Sanguinetti, Maurizio, McInnes, Iain B., McSharry, Charles, Gasbarrini, Antonio, Otto, Thomas D., Kurowska-Stolarska, Mariola, Gremese, Elisa
Publicat a JCI Insight (2021)