Sphingosine Kinases promote IL-17 expression in human T lymphocytes

Sphingosine 1-phosphate (S1P) has a role in many cellular processes. S1P is involved in cell growth and apoptosis, regulation of cell trafficking, production of cytokines and chemokines. The kinases SphK1 and SphK2 (SphKs) phosphorilate Sphingosine (Sph) to S1P and several phosphatases revert S1P to...

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Vydáno v:Sci Rep
Hlavní autoři: Barra, Giusi, Lepore, Alessio, Gagliardi, Miriam, Somma, Domenico, Matarazzo, Maria Rosaria, Costabile, Francesca, Pasquale, Giuseppe, Mazzoni, Alessio, Gallo, Carmela, Nuzzo, Genoveffa, Annunziato, Francesco, Fontana, Angelo, Leonardi, Antonio, De Palma, Raffaele
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125344/
https://ncbi.nlm.nih.gov/pubmed/30185808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31666-1
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