Sphingosine Kinases promote IL-17 expression in human T lymphocytes

Sphingosine 1-phosphate (S1P) has a role in many cellular processes. S1P is involved in cell growth and apoptosis, regulation of cell trafficking, production of cytokines and chemokines. The kinases SphK1 and SphK2 (SphKs) phosphorilate Sphingosine (Sph) to S1P and several phosphatases revert S1P to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barra, Giusi, Lepore, Alessio, Gagliardi, Miriam, Somma, Domenico, Matarazzo, Maria Rosaria, Costabile, Francesca, Pasquale, Giuseppe, Mazzoni, Alessio, Gallo, Carmela, Nuzzo, Genoveffa, Annunziato, Francesco, Fontana, Angelo, Leonardi, Antonio, De Palma, Raffaele
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125344/
https://ncbi.nlm.nih.gov/pubmed/30185808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31666-1
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