Biology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview.

av McCann, Tyler S., Sobral, Lays M., Self, Chelsea, Hsieh, Joseph, Sechler, Marybeth, Jedlicka, Paul
I publikationen Expert Opin Ther Targets (2019)

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survi...

av Parrish, Janet K., McCann, Tyler S., Sechler, Marybeth, Sobral, Lays M., Ren, Wenhua, Jones, Kenneth L., Tan, Aik Choon, Jedlicka, Paul
I publikationen Oncotarget (2018)

KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1‐driven and independent disease‐promoting gene expression in fusion‐positive Rhabdomyosarcoma

av Sobral, Lays M., Hicks, Hannah M., Parrish, Janet K., McCann, Tyler S., Hsieh, Joseph, Goodspeed, Andrew, Costello, James C., Black, Joshua C., Jedlicka, Paul
I publikationen Mol Oncol (2020)

Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lym...

av Sobral, Lays M, Sousa, Lucas O, Coletta, Ricardo D, Cabral, Hamilton, Greene, Lewis J, Tajara, Eloiza H, Gutkind, J Silvio, Curti, Carlos, Leopoldino, Andréia M
Publicerad 2014

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma

av McCann, Tyler S., Parrish, Janet K., Hsieh, Joseph, Sechler, Marybeth, Sobral, Lays M., Self, Chelsea, Jones, Kenneth L., Goodspeed, Andrew, Costello, James C., Jedlicka, Paul
I publikationen Oncotarget (2020)

Lymph node or perineural invasion is associated with low miR-15a, miR-34c and miR-199b levels in head and neck squamous cell carcinoma

av Sousa, Lucas O., Sobral, Lays M., Matsumoto, Camila S., Saggioro, Fabiano P., López, Rossana V.M., Panepucci, Rodrigo A., Curti, Carlos, Silva, Wilson A., Greene, Lewis J., Leopoldino, Andréia M.
I publikationen BBA Clin (2016)

Proteomic Approaches Identify Members of Cofilin Pathway Involved in Oral Tumorigenesis

av Polachini, Giovana M., Sobral, Lays M., Mercante, Ana M. C., Paes-Leme, Adriana F., Xavier, Flávia C. A., Henrique, Tiago, Guimarães, Douglas M., Vidotto, Alessandra, Fukuyama, Erica E., Góis-Filho, José F., Cury, Patricia M., Curioni, Otávio A., Michaluart Jr, Pedro, Silva, Adriana M. A., Wünsch-Filho, Victor, Nunes, Fabio D., Leopoldino, Andréia M., Tajara, Eloiza H.
Publicerad 2012