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Biology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview.
INTRODUCTION: Epigenetic mechanisms of gene regulatory control play fundamental roles in developmental morphogenesis, and, as more recently appreciated, are heavily implicated in the onset and progression of neoplastic disease, including cancer. Many epigenetic mechanisms are therapeutically targeta...
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| Publicado no: | Expert Opin Ther Targets |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509558/ https://ncbi.nlm.nih.gov/pubmed/30759030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2019.1580692 |
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