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The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis

Ewing Sarcoma is the second most common solid pediatric malignant neoplasm of bone and soft tissue. Driven by EWS/Ets, or rarely variant, oncogenic fusions, Ewing Sarcoma is a biologically and clinically aggressive disease with a high propensity for metastasis. However, the mechanisms underpinning E...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Sechler, Marybeth, Parrish, Janet K., Birks, Diane K., Jedlicka, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519422/
https://ncbi.nlm.nih.gov/pubmed/28319067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.44
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