Biology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview.

Por McCann, Tyler S., Sobral, Lays M., Self, Chelsea, Hsieh, Joseph, Sechler, Marybeth, Jedlicka, Paul
Publicado no Expert Opin Ther Targets (2019)

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survi...

Por Parrish, Janet K., McCann, Tyler S., Sechler, Marybeth, Sobral, Lays M., Ren, Wenhua, Jones, Kenneth L., Tan, Aik Choon, Jedlicka, Paul
Publicado no Oncotarget (2018)

KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1‐driven and independent disease‐promoting gene expression in fusion‐positive Rhabdomyosarcoma

Por Sobral, Lays M., Hicks, Hannah M., Parrish, Janet K., McCann, Tyler S., Hsieh, Joseph, Goodspeed, Andrew, Costello, James C., Black, Joshua C., Jedlicka, Paul
Publicado no Mol Oncol (2020)

Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lym...

Por Sobral, Lays M, Sousa, Lucas O, Coletta, Ricardo D, Cabral, Hamilton, Greene, Lewis J, Tajara, Eloiza H, Gutkind, J Silvio, Curti, Carlos, Leopoldino, Andréia M
Publicado em 2014

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma

Por McCann, Tyler S., Parrish, Janet K., Hsieh, Joseph, Sechler, Marybeth, Sobral, Lays M., Self, Chelsea, Jones, Kenneth L., Goodspeed, Andrew, Costello, James C., Jedlicka, Paul
Publicado no Oncotarget (2020)

Lymph node or perineural invasion is associated with low miR-15a, miR-34c and miR-199b levels in head and neck squamous cell carcinoma

Por Sousa, Lucas O., Sobral, Lays M., Matsumoto, Camila S., Saggioro, Fabiano P., López, Rossana V.M., Panepucci, Rodrigo A., Curti, Carlos, Silva, Wilson A., Greene, Lewis J., Leopoldino, Andréia M.
Publicado no BBA Clin (2016)

Proteomic Approaches Identify Members of Cofilin Pathway Involved in Oral Tumorigenesis

Por Polachini, Giovana M., Sobral, Lays M., Mercante, Ana M. C., Paes-Leme, Adriana F., Xavier, Flávia C. A., Henrique, Tiago, Guimarães, Douglas M., Vidotto, Alessandra, Fukuyama, Erica E., Góis-Filho, José F., Cury, Patricia M., Curioni, Otávio A., Michaluart Jr, Pedro, Silva, Adriana M. A., Wünsch-Filho, Victor, Nunes, Fabio D., Leopoldino, Andréia M., Tajara, Eloiza H.
Publicado em 2012