Biology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview.

per McCann, Tyler S., Sobral, Lays M., Self, Chelsea, Hsieh, Joseph, Sechler, Marybeth, Jedlicka, Paul
Publicat a Expert Opin Ther Targets (2019)

The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survi...

per Parrish, Janet K., McCann, Tyler S., Sechler, Marybeth, Sobral, Lays M., Ren, Wenhua, Jones, Kenneth L., Tan, Aik Choon, Jedlicka, Paul
Publicat a Oncotarget (2018)

KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1‐driven and independent disease‐promoting gene expression in fusion‐positive Rhabdomyosarcoma

per Sobral, Lays M., Hicks, Hannah M., Parrish, Janet K., McCann, Tyler S., Hsieh, Joseph, Goodspeed, Andrew, Costello, James C., Black, Joshua C., Jedlicka, Paul
Publicat a Mol Oncol (2020)

Stable SET knockdown in head and neck squamous cell carcinoma promotes cell invasion and the mesenchymal-like phenotype in vitro, as well as necrosis, cisplatin sensitivity and lym...

per Sobral, Lays M, Sousa, Lucas O, Coletta, Ricardo D, Cabral, Hamilton, Greene, Lewis J, Tajara, Eloiza H, Gutkind, J Silvio, Curti, Carlos, Leopoldino, Andréia M
Publicat 2014

KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing sarcoma

per McCann, Tyler S., Parrish, Janet K., Hsieh, Joseph, Sechler, Marybeth, Sobral, Lays M., Self, Chelsea, Jones, Kenneth L., Goodspeed, Andrew, Costello, James C., Jedlicka, Paul
Publicat a Oncotarget (2020)

Lymph node or perineural invasion is associated with low miR-15a, miR-34c and miR-199b levels in head and neck squamous cell carcinoma

per Sousa, Lucas O., Sobral, Lays M., Matsumoto, Camila S., Saggioro, Fabiano P., López, Rossana V.M., Panepucci, Rodrigo A., Curti, Carlos, Silva, Wilson A., Greene, Lewis J., Leopoldino, Andréia M.
Publicat a BBA Clin (2016)

Proteomic Approaches Identify Members of Cofilin Pathway Involved in Oral Tumorigenesis

per Polachini, Giovana M., Sobral, Lays M., Mercante, Ana M. C., Paes-Leme, Adriana F., Xavier, Flávia C. A., Henrique, Tiago, Guimarães, Douglas M., Vidotto, Alessandra, Fukuyama, Erica E., Góis-Filho, José F., Cury, Patricia M., Curioni, Otávio A., Michaluart Jr, Pedro, Silva, Adriana M. A., Wünsch-Filho, Victor, Nunes, Fabio D., Leopoldino, Andréia M., Tajara, Eloiza H.
Publicat 2012