Fine mapping of the latency-related gene of herpes simplex virus type 1: alternative splicing produces distinct latency-related RNAs containing open reading frames.

por Wechsler, S L, Nesburn, A B, Watson, R, Slanina, S M, Ghiasi, H
Publicado em 1988

The spontaneous reactivation function of the herpes simplex virus type 1 LAT gene resides completely within the first 1.5 kilobases of the 8.3-kilobase primary transcript.

por Perng, G C, Ghiasi, H, Slanina, S M, Nesburn, A B, Wechsler, S L
Publicado em 1996

A 371-nucleotide region between the herpes simplex virus type 1 (HSV-1) LAT promoter and the 2-kilobase LAT is not essential for efficient spontaneous reactivation of latent HSV-1.

por Perng, G C, Slanina, S M, Ghiasi, H, Nesburn, A B, Wechsler, S L
Publicado em 1996

High-dose ocular infection with a herpes simplex virus type 1 ICP34.5 deletion mutant produces no corneal disease or neurovirulence yet results in wild-type levels of spontaneous r...

por Perng, G C, Ghiasi, H, Slanina, S M, Nesburn, A B, Wechsler, S L
Publicado em 1996

The Latency-Associated Transcript Gene Enhances Establishment of Herpes Simplex Virus Type 1 Latency in Rabbits

por Perng, Guey-Chuen, Slanina, Susan M., Yukht, Ada, Ghiasi, Homayon, Nesburn, Anthony B., Wechsler, Steven L.
Publicado em 2000

Herpes Simplex Virus Type 1 Serum Neutralizing Antibody Titers Increase during Latency in Rabbits Latently Infected with Latency-Associated Transcript (LAT)-Positive but Not LAT-Ne...

por Perng, Guey-Chuen, Slanina, Susan M., Yukht, Ada, Ghiasi, Homayon, Nesburn, Anthony B., Wechsler, Steven L.
Publicado em 1999

A Herpes Simplex Virus Type 1 Latency-Associated Transcript Mutant with Increased Virulence and Reduced Spontaneous Reactivation

por Perng, Guey-Chuen, Slanina, Susan M., Yukht, Ada, Drolet, Barbara S., Keleher, William, Ghiasi, Homayon, Nesburn, Anthony B., Wechsler, Steven L.
Publicado em 1999

The region of the herpes simplex virus type 1 LAT gene that is colinear with the ICP34.5 gene is not involved in spontaneous reactivation.

por Perng, G C, Chokephaibulkit, K, Thompson, R L, Sawtell, N M, Slanina, S M, Ghiasi, H, Nesburn, A B, Wechsler, S L
Publicado em 1996

The latency-associated transcript gene of herpes simplex virus type 1 (HSV-1) is required for efficient in vivo spontaneous reactivation of HSV-1 from latency.

por Perng, G C, Dunkel, E C, Geary, P A, Slanina, S M, Ghiasi, H, Kaiwar, R, Nesburn, A B, Wechsler, S L
Publicado em 1994

Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript.

por Zwaagstra, J C, Ghiasi, H, Slanina, S M, Nesburn, A B, Wheatley, S C, Lillycrop, K, Wood, J, Latchman, D S, Patel, K, Wechsler, S L
Publicado em 1990

An avirulent ICP34.5 deletion mutant of herpes simplex virus type 1 is capable of in vivo spontaneous reactivation.

por Perng, G C, Thompson, R L, Sawtell, N M, Taylor, W E, Slanina, S M, Ghiasi, H, Kaiwar, R, Nesburn, A B, Wechsler, S L
Publicado em 1995

Three Herpes Simplex Virus Type 1 Latency-Associated Transcript Mutants with Distinct and Asymmetric Effects on Virulence in Mice Compared with Rabbits

por Perng, Guey-Chuen, Esmaili, Daniel, Slanina, Susan M., Yukht, Ada, Ghiasi, Homayon, Osorio, Nelson, Mott, Kevin R., Maguen, Barak, Jin, Ling, Nesburn, Anthony B., Wechsler, Steven L.
Publicado em 2001

A Gene Capable of Blocking Apoptosis Can Substitute for the Herpes Simplex Virus Type 1 Latency-Associated Transcript Gene and Restore Wild-Type Reactivation Levels

por Perng, Guey-Chuen, Maguen, Barak, Jin, Ling, Mott, Kevin R., Osorio, Nelson, Slanina, Susan M., Yukht, Ada, Ghiasi, Homayon, Nesburn, Anthony B., Inman, Melissa, Henderson, Gail, Jones, Clinton, Wechsler, Steven L.
Publicado em 2002