Leptin increasing sympathetic nerve outflow in obesity: A cure for obesity or a potential contributor to metabolic syndrome?

Por Simonds, Stephanie E., Cowley, Michael A., Enriori, Pablo J.
Publicado em 2012

Leptin reduces food intake via a dopamine D2 receptor-dependent mechanism

Por Billes, Sonja K., Simonds, Stephanie E., Cowley, Michael A.
Publicado em 2012

Leptin Action in the Dorsomedial Hypothalamus Increases Sympathetic Tone to Brown Adipose Tissue in Spite of Systemic Leptin Resistance

Por Enriori, Pablo J., Sinnayah, Puspha, Simonds, Stephanie E., Garcia Rudaz, Cecilia, Cowley, Michael A.
Publicado em 2011

Impaired kisspeptin signaling decreases metabolism and promotes glucose intolerance and obesity

Por Tolson, Kristen P., Garcia, Christian, Yen, Stephanie, Simonds, Stephanie, Stefanidis, Aneta, Lawrence, Alison, Smith, Jeremy T., Kauffman, Alexander S.
Publicado em 2014

Leptin Stimulates Neuropeptide Y and Cocaine Amphetamine-Regulated Transcript Coexpressing Neuronal Activity in the Dorsomedial Hypothalamus in Diet-Induced Obese Mice

Por Lee, Shin J., Verma, Saurabh, Simonds, Stephanie E., Kirigiti, Melissa A., Kievit, Paul, Lindsley, Sarah R., Loche, Alberto, Smith, M. Susan, Cowley, Michael A., Grove, Kevin L.
Publicado em 2013

Addiction-like synaptic impairments in diet-induced obesity

Por Brown, Robyn Mary, Kupchik, Yonatan Michael, Spencer, Sade, Garcia-Keller, Constanza, Spanswick, David C, Lawrence, Andrew John, Simonds, Stephanie Elise, Schwartz, Danielle Joy, Jordan, Kelsey Ann, Jhou, Thomas Clayton, Kalivas, Peter William
Publicado no Biol Psychiatry (2015)

Leptin and insulin act on POMC neurons to promote the browning of white fat

Por Dodd, Garron, Descherf, Stephanie, Loh, Kim, Simonds, Stephanie E., Wiede, Florian, Balland, Eglantine, Merry, Troy L., Münzberg, Heike, Zhang, Zhong-Yin, Kahn, Barbara B., Neel, Benjamin G., Bence, Kendra K., Andrews, Zane B., Cowley, Michael A., Tiganis, Tony
Publicado no Cell (2015)

Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance

Por Loh, Kim, Fukushima, Atsushi, Zhang, Xinmei, Galic, Sandra, Briggs, Dana, Enriori, Pablo J., Simonds, Stephanie, Wiede, Florian, Reichenbach, Alexander, Hauser, Christine, Sims, Natalie A., Bence, Kendra K., Zhang, Sheng, Zhang, Zhong-Yin, Kahn, Barbara B., Neel, Benjamin G., Andrews, Zane B., Cowley, Michael A., Tiganis, Tony
Publicado em 2011

Hypothalamic POMC neurons promote cannabinoid-induced feeding

Por Koch, Marco, Varela, Luis, Kim, Jae Geun, Kim, Jung Dae, Hernandez, Francisco, Simonds, Stephanie E, Castorena, Carlos M, Vianna, Claudia R, Elmquist, Joel K, Morozov, Yury M, Rakic, Pasko, Bechmann, Ingo, Cowley, Michael A, Szigeti-Buck, Klara, Dietrich, Marcelo O, Gao, Xiao-Bing, Diano, Sabrina, Horvath, Tamas L
Publicado no Nature (2015)

Leptin Mediates the Increase in Blood Pressure Associated with Obesity

Por Simonds, Stephanie E., Pryor, Jack T., Ravussin, Eric, Greenway, Frank L., Dileone, Ralph, Allen, Andrew M., Bassi, Jaspreet, Elmquist, Joel K., Keogh, Julia M., Henning, Elana, Myers, Martin G., Licinio, Julio, Brown, Russell D., Enriori, Pablo J., O’Rahilly, Stephen, Sternson, Scott M., Grove, Kevin L., Spanswick, David C., Farooqi, I. Sadaf, Cowley, Michael A.
Publicado no Cell (2014)

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling

Por Furtado, Milena B., Wilmanns, Julia C., Chandran, Anjana, Perera, Joelle, Hon, Olivia, Biben, Christine, Willow, Taylor J., Nim, Hieu T., Kaur, Gurpreet, Simonds, Stephanie, Wu, Qizhu, Willians, David, Salimova, Ekaterina, Plachta, Nicolas, Denegre, James M., Murray, Stephen A., Fatkin, Diane, Cowley, Michael, Pearson, James T., Kaye, David, Ramialison, Mirana, Harvey, Richard P., Rosenthal, Nadia A., Costa, Mauro W.
Publicado no JCI Insight (2017)

α-Melanocyte stimulating hormone promotes muscle glucose uptake via melanocortin 5 receptors

Por Enriori, Pablo J., Chen, Weiyi, Garcia-Rudaz, Maria C., Grayson, Bernadette E., Evans, Anne E., Comstock, Sarah M., Gebhardt, Ursel, Müller, Hermann L., Reinehr, Thomas, Henry, Belinda A., Brown, Russell D., Bruce, Clinton R., Simonds, Stephanie E., Litwak, Sara A., McGee, Sean L., Luquet, Serge, Martinez, Sarah, Jastroch, Martin, Tschöp, Matthias H., Watt, Matthew J., Clarke, Iain J., Roth, Christian L., Grove, Kevin L., Cowley, Michael A.
Publicado no Mol Metab (2016)