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Leptin Mediates the Increase in Blood Pressure Associated with Obesity

Obesity is associated with increased blood pressure (BP), which in turn increases the risk of cardiovascular diseases. We found that the increase in leptin levels seen in diet-induced obesity (DIO) drives an increase in BP in rodents, an effect that was not seen in animals deficient in leptin or lep...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Simonds, Stephanie E., Pryor, Jack T., Ravussin, Eric, Greenway, Frank L., Dileone, Ralph, Allen, Andrew M., Bassi, Jaspreet, Elmquist, Joel K., Keogh, Julia M., Henning, Elana, Myers, Martin G., Licinio, Julio, Brown, Russell D., Enriori, Pablo J., O’Rahilly, Stephen, Sternson, Scott M., Grove, Kevin L., Spanswick, David C., Farooqi, I. Sadaf, Cowley, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259491/
https://ncbi.nlm.nih.gov/pubmed/25480301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.058
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