ATRP in the design of functional materials for biomedical applications

по Siegwart, Daniel J., Oh, Jung Kwon, Matyjaszewski, Krzysztof
Опубликовано 2011

Strategies, Design, and Chemistry in siRNA Delivery Systems

по Dong, Yizhou, Siegwart, Daniel J., Anderson, Daniel G.
Опубликовано в: Adv Drug Deliv Rev (2019)

Automated ARGET ATRP Accelerates Catalyst Optimization for the Synthesis of Thiol-Functionalized Polymers

по Siegwart, Daniel J., Leiendecker, Matthias, Langer, Robert, Anderson, Daniel G.
Опубликовано 2012

Degradable Redox-Responsive Disulfide-Based Nanogel Drug Carriers via Dithiol Oxidation Polymerization

по Elkassih, Sussana A., Kos, Petra, Xiong, Hu, Siegwart, Daniel J.
Опубликовано в: Biomater Sci (2019)

Theranostic dendrimer-based lipid nanoparticles containing PEGylated BODIPY dyes for tumor imaging and systemic mRNA delivery in vivo

по Xiong, Hu, Liu, Shuai, Wei, Tuo, Cheng, Qiang, Siegwart, Daniel J.
Опубликовано в: J Control Release (2020)

Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing

по Wei, Tuo, Cheng, Qiang, Min, Yi-Li, Olson, Eric N., Siegwart, Daniel J.
Опубликовано в: Nat Commun (2020)

Selective ORgan Targeting (SORT) nanoparticles for tissue specific mRNA delivery and CRISPR/Cas gene editing

по Cheng, Qiang, Wei, Tuo, Farbiak, Lukas, Johnson, Lindsay T., Dilliard, Sean A., Siegwart, Daniel J.
Опубликовано в: Nat Nanotechnol (2020)

Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for in Vivo CRISPR/Cas-Based Genome Editing

по Wei, Tuo, Cheng, Qiang, Farbiak, Lukas, Anderson, Daniel G., Langer, Robert, Siegwart, Daniel J.
Опубликовано в: ACS Nano (2020)

A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo

по Lee, Sang M., Cheng, Qiang, Yu, Xueliang, Liu, Shuai, Johnson, Lindsay T., Siegwart, Daniel J.
Опубликовано в: Angew Chem Int Ed Engl (2021)

Lipid-modified Aminoglycosides for mRNA Delivery to the Liver

по Yu, Xueliang, Liu, Shuai, Cheng, Qiang, Wei, Tuo, Lee, Sang, Zhang, Di, Siegwart, Daniel J.
Опубликовано в: Adv Healthc Mater (2020)

Membrane destabilizing ionizable phospholipids for organ selective mRNA delivery and CRISPR/Cas gene editing

по Liu, Shuai, Cheng, Qiang, Wei, Tuo, Yu, Xueliang, Johnson, Lindsay T., Farbiak, Lukas, Siegwart, Daniel J.
Опубликовано в: Nat Mater (2021)

Effect of molecular weight of amine end-modified poly(β-amino ester)s on gene delivery efficiency and toxicity

по Eltoukhy, Ahmed A., Siegwart, Daniel J., Alabi, Christopher A., Rajan, Jay S., Langer, Robert, Anderson, Daniel G.
Опубликовано 2012

Nanostructured hybrid hydrogels prepared by a combination of atom transfer radical polymerization and free radical polymerization

по Bencherif, Sidi A., Siegwart, Daniel J., Srinivasan, Abiraman, Horkay, Ferenc, Hollinger, Jeffrey O., Washburn, Newell R., Matyjaszewski, Krzysztof
Опубликовано 2009

Gpr132 sensing of lactate mediates tumor–macrophage interplay to promote breast cancer metastasis

по Chen, Peiwen, Zuo, Hao, Xiong, Hu, Kolar, Matthew J., Chu, Qian, Saghatelian, Alan, Siegwart, Daniel J., Wan, Yihong
Опубликовано в: Proc Natl Acad Sci U S A (2017)

Non-viral CRISPR/Cas gene editing in vitro and in vivo enabled by synthetic nanoparticle co-delivery of Cas9 mRNA and sgRNA

по Miller, Jason B., Zhang, Shuyuan, Kos, Petra, Xiong, Hu, Zhou, Kejin, Perelman, Sofya S., Zhu, Hao, Siegwart, Daniel J.
Опубликовано в: Angew Chem Int Ed Engl (2016)

HDAC Inhibitor Conjugated Polymeric Prodrug Micelles for Doxorubicin Delivery

по Senevirathne, Suchithra A., Washington, Katherine E., Miller, Jason B., Biewer, Michael C., Oupicky, David, Siegwart, Daniel J., Stefan, Mihaela C.
Опубликовано в: J Mater Chem B Mater Biol Med (2017)

Development of Cationic Polymer Coatings to Regulate Foreign Body Responses

по Ma, Minglin, Liu, Wendy F., Hill, Paulina S., Bratlie, Kaitlin M., Siegwart, Daniel J., Chin, Justin, Park, Miri, Guerreiro, Joao, Anderson, Daniel G.
Опубликовано 2011

One-pot Synthesis of Functional Poly(amino ester sulfide)s and Utility in Delivering pDNA and siRNA

по Yan, Yunfeng, Xue, Lian, Miller, Jason B., Zhou, Kejin, Kos, Petra, Elkassih, Sussana, Liu, Li, Nagai, Atsushi, Xiong, Hu, Siegwart, Daniel J.
Опубликовано в: Polymer (Guildf) (2015)

Cellular uptake of functional nanogels prepared by inverse miniemulsion ATRP with encapsulated proteins, carbohydrates, and gold nanoparticles

по Siegwart, Daniel J., Srinivasan, Abiraman, Bencherif, Sidi A., Karunanidhi, Anuradha, Oh, Jung Kwon, Vaidya, Swaroopa, Jin, Rongchao, Hollinger, Jeffrey O., Matyjaszewski, Krzysztof
Опубликовано в: Biomacromolecules (2009)

A Novel Family of Biodegradable Poly(ester amide) Elastomers

по Cheng, Hao, Hill, Paulina S., Siegwart, Daniel J., Vacanti, Nathaniel, Lytton-Jean, Abigail K. R., Cho, Seung-Woo, Ye, Anne, Langer, Robert, Anderson, Daniel G.
Опубликовано 2011