Efficient Suppression of Hepatitis C Virus Replication by Combination Treatment with miR-122 Antagonism and Direct-acting Antivirals in Cell Culture Systems

Tekijä Liu, Fanwei, Shimakami, Tetsuro, Murai, Kazuhisa, Shirasaki, Takayoshi, Funaki, Masaya, Honda, Masao, Murakami, Seishi, Yi, Minkyung, Tang, Hong, Kaneko, Shuichi
Julkaisussa Sci Rep (2016)

Inhibition of microRNA-214 ameliorates hepatic fibrosis and tumor incidence in platelet-derived growth factor C transgenic mice

Tekijä Okada, Hikari, Honda, Masao, Campbell, Jean S, Takegoshi, Kai, Sakai, Yoshio, Yamashita, Taro, Shirasaki, Takayoshi, Takabatake, Riuta, Nakamura, Mikiko, Tanaka, Takuji, Kaneko, Shuichi
Julkaisussa Cancer Sci (2015)

Peretinoin, an Acyclic Retinoid, Inhibits Hepatitis B Virus Replication by Suppressing Sphingosine Metabolic Pathway In Vitro

Tekijä Murai, Kazuhisa, Shirasaki, Takayoshi, Honda, Masao, Shimizu, Ryogo, Shimakami, Tetsuro, Nakasho, Saki, Shirasaki, Natsumi, Okada, Hikari, Sakai, Yoshio, Yamashita, Taro, Kaneko, Shuichi
Julkaisussa Int J Mol Sci (2018)

Establishment of liver tumor cell lines from atherogenic and high fat diet fed hepatitis C virus transgenic mice

Tekijä Shirasaki, Takayoshi, Murai, Kazuhisa, Honda, Masao, Okada, Hikari, Innami, Yuika, Yamada, Atsumu, Shimakami, Tetsuro, Kawaguchi, Kazunori, Yamashita, Taro, Sakai, Yoshio, Kaneko, Shuichi
Julkaisussa Sci Rep (2021)

The Acyclic Retinoid Peretinoin Inhibits Hepatitis C Virus Replication and Infectious Virus Release in Vitro

Tekijä Shimakami, Tetsuro, Honda, Masao, Shirasaki, Takayoshi, Takabatake, Riuta, Liu, Fanwei, Murai, Kazuhisa, Shiomoto, Takayuki, Funaki, Masaya, Yamane, Daisuke, Murakami, Seishi, Lemon, Stanley M., Kaneko, Shuichi
Julkaistu 2014

Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet

Tekijä Okada, Hikari, Takabatake, Riuta, Honda, Masao, Takegoshi, Kai, Yamashita, Taro, Nakamura, Mikiko, Shirasaki, Takayoshi, Sakai, Yoshio, Shimakami, Tetsuro, Nagata, Naoto, Takamura, Toshinari, Tanaka, Takuji, Kaneko, Shuichi
Julkaisussa Oncotarget (2017)

Unexpected Replication Boost by Simeprevir for Simeprevir-Resistant Variants in Genotype 1a Hepatitis C Virus

Tekijä Murai, Kazuhisa, Shimakami, Tetsuro, Welsch, Christoph, Shirasaki, Takayoshi, Liu, Fanwei, Kitabayashi, Juria, Tanaka, Shiho, Funaki, Masaya, Omura, Hitoshi, Nishikawa, Tomoki, Sumiyadorj, Ariunaa, Honda, Masao, Kaneko, Shuichi
Julkaisussa Antimicrob Agents Chemother (2018)

Notch signaling facilitates hepatitis B virus covalently closed circular DNA transcription via cAMP response element-binding protein with E3 ubiquitin ligase-modulation

Tekijä Wang, Zijing, Kawaguchi, Kazunori, Honda, Masao, Hashimoto, Shinichi, Shirasaki, Takayoshi, Okada, Hikari, Orita, Noriaki, Shimakami, Tetsuro, Yamashita, Taro, Sakai, Yoshio, Mizukoshi, Eishiro, Murakami, Seishi, Kaneko, Shuichi
Julkaisussa Sci Rep (2019)

MicroRNA-27a Regulates Lipid Metabolism and Inhibits Hepatitis C Virus Replication in Human Hepatoma Cells

Tekijä Shirasaki, Takayoshi, Honda, Masao, Shimakami, Tetsuro, Horii, Rika, Yamashita, Taro, Sakai, Yoshio, Sakai, Akito, Okada, Hikari, Watanabe, Risa, Murakami, Seishi, Yi, MinKyung, Lemon, Stanley M., Kaneko, Shuichi
Julkaistu 2013

Establishment and Characterization of a New Cell Line Permissive for Hepatitis C Virus Infection

Tekijä Omura, Hitoshi, Liu, Fanwei, Shimakami, Tetsuro, Murai, Kazuhisa, Shirasaki, Takayoshi, Kitabayashi, Juria, Funaki, Masaya, Nishikawa, Tomoki, Nakai, Ryotaro, Sumiyadorj, Ariunaa, Hayashi, Takehiro, Yamashita, Taro, Honda, Masao, Kaneko, Shuichi
Julkaisussa Sci Rep (2019)

Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model

Tekijä Takegoshi, Kai, Honda, Masao, Okada, Hikari, Takabatake, Riuta, Matsuzawa-Nagata, Naoto, Campbell, Jean S., Nishikawa, Masashi, Shimakami, Tetsuro, Shirasaki, Takayoshi, Sakai, Yoshio, Yamashita, Taro, Takamura, Toshinari, Tanaka, Takuji, Kaneko, Shuichi
Julkaisussa Oncotarget (2017)

Peretinoin, an acyclic retinoid, inhibits hepatocarcinogenesis by suppressing sphingosine kinase 1 expression in vitro and in vivo

Tekijä Funaki, Masaya, Kitabayashi, Juria, Shimakami, Tetsuro, Nagata, Naoto, Sakai, Yuriko, Takegoshi, Kai, Okada, Hikari, Murai, Kazuhisa, Shirasaki, Takayoshi, Oyama, Takeru, Yamashita, Taro, Ota, Tsuguhito, Takuwa, Yoh, Honda, Masao, Kaneko, Shuichi
Julkaisussa Sci Rep (2017)

The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication

Tekijä Shirasaki, Takayoshi, Honda, Masao, Yamashita, Taro, Nio, Kouki, Shimakami, Tetsuro, Shimizu, Ryougo, Nakasyo, Saki, Murai, Kazuhisa, Shirasaki, Natsumi, Okada, Hikari, Sakai, Yoshio, Sato, Tokiharu, Suzuki, Tetsuro, Yoshioka, Katsuji, Kaneko, Shuichi
Julkaisussa Sci Rep (2018)

Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C

Tekijä Selitsky, Sara R., Baran-Gale, Jeanette, Honda, Masao, Yamane, Daisuke, Masaki, Takahiro, Fannin, Emily E., Guerra, Bernadette, Shirasaki, Takayoshi, Shimakami, Tetsuro, Kaneko, Shuichi, Lanford, Robert E., Lemon, Stanley M., Sethupathy, Praveen
Julkaisussa Sci Rep (2015)

MicroRNA‐10a Impairs Liver Metabolism in Hepatitis C Virus‐Related Cirrhosis Through Deregulation of the Circadian Clock Gene Brain and Muscle Aryl Hydrocarbon Receptor Nuclear Tra...

Tekijä Horii, Rika, Honda, Masao, Shirasaki, Takayoshi, Shimakami, Tetsuro, Shimizu, Ryogo, Yamanaka, Souma, Murai, Kazuhisa, Kawaguchi, Kazunori, Arai, Kuniaki, Yamashita, Tatsuya, Sakai, Yoshio, Yamashita, Taro, Okada, Hikari, Nakamura, Mikiko, Mizukoshi, Eishiro, Kaneko, Shuichi
Julkaisussa Hepatol Commun (2019)

DOCK11 and DENND2A play pivotal roles in the maintenance of hepatitis B virus in host cells

Tekijä Hashimoto, Shinichi, Shirasaki, Takayoshi, Yamashita, Taro, Iwabuchi, Sadahiro, Suzuki, Yutaka, Takamura, Yuzuru, Ukita, Yoshiaki, Deshimaru, Shungo, Okayama, Toshitugu, Ikeo, Kazuho, Kuroki, Kazuyuki, Kawaguchi, Kazunori, Mizukoshi, Eishiro, Matsushima, Kouji, Honda, Masao, Kaneko, Shuichi
Julkaisussa PLoS One (2021)

Metformin Suppresses Expression of the Selenoprotein P Gene via an AMP-activated Kinase (AMPK)/FoxO3a Pathway in H4IIEC3 Hepatocytes

Tekijä Takayama, Hiroaki, Misu, Hirofumi, Iwama, Hisakazu, Chikamoto, Keita, Saito, Yoshiro, Murao, Koji, Teraguchi, Atsushi, Lan, Fei, Kikuchi, Akihiro, Saito, Reina, Tajima, Natsumi, Shirasaki, Takayoshi, Matsugo, Seiichi, Miyamoto, Ken-ichi, Kaneko, Shuichi, Takamura, Toshinari
Julkaistu 2014

Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepa...

Tekijä Tajima-Shirasaki, Natsumi, Ishii, Kiyo-aki, Takayama, Hiroaki, Shirasaki, Takayoshi, Iwama, Hisakazu, Chikamoto, Keita, Saito, Yoshiro, Iwasaki, Yasumasa, Teraguchi, Atsushi, Lan, Fei, Kikuchi, Akihiro, Takeshita, Yumie, Murao, Koji, Matsugo, Seiichi, Kaneko, Shuichi, Misu, Hirofumi, Takamura, Toshinari
Julkaisussa J Biol Chem (2017)

Induction of IFN-λ3 as an additional effect of nucleotide, not nucleoside, analogues: a new potential target for HBV infection

Tekijä Murata, Kazumoto, Asano, Mai, Matsumoto, Akihiro, Sugiyama, Masaya, Nishida, Nao, Tanaka, Eiji, Inoue, Taisuke, Sakamoto, Minoru, Enomoto, Nobuyuki, Shirasaki, Takayoshi, Honda, Masao, Kaneko, Shuichi, Gatanaga, Hiroyuki, Oka, Shinichi, Kawamura, Yuki I, Dohi, Taeko, Shuno, Yasutaka, Yano, Hideaki, Mizokami, Masashi
Julkaisussa Gut (2018)