Peretinoin, an acyclic retinoid, suppresses steatohepatitis and tumorigenesis by activating autophagy in mice fed an atherogenic high-fat diet

The pathogenesis of non-alcoholic steatohepatitis (NASH) is still unclear and the prevention of the development of hepatocellular carcinoma (HCC) has not been established. We established an atherogenic and high-fat diet mouse model that develops hepatic steatosis, inflammation, fibrosis, and liver t...

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Udgivet i:Oncotarget
Main Authors: Okada, Hikari, Takabatake, Riuta, Honda, Masao, Takegoshi, Kai, Yamashita, Taro, Nakamura, Mikiko, Shirasaki, Takayoshi, Sakai, Yoshio, Shimakami, Tetsuro, Nagata, Naoto, Takamura, Toshinari, Tanaka, Takuji, Kaneko, Shuichi
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Priority Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522259/
https://ncbi.nlm.nih.gov/pubmed/28591717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18116
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