The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication

Osteopontin (OPN) is involved in cell proliferation, migration, inflammation, and tumor progression in various tissues. OPN induces stemness by interacting with CD44, but the functional relevance of OPN-mediated interferon (IFN) signaling and hepatitis C virus (HCV) replication in stem cell populati...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Shirasaki, Takayoshi, Honda, Masao, Yamashita, Taro, Nio, Kouki, Shimakami, Tetsuro, Shimizu, Ryougo, Nakasyo, Saki, Murai, Kazuhisa, Shirasaki, Natsumi, Okada, Hikari, Sakai, Yoshio, Sato, Tokiharu, Suzuki, Tetsuro, Yoshioka, Katsuji, Kaneko, Shuichi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120883/
https://ncbi.nlm.nih.gov/pubmed/30177680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31421-6
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