The osteopontin-CD44 axis in hepatic cancer stem cells regulates IFN signaling and HCV replication

Osteopontin (OPN) is involved in cell proliferation, migration, inflammation, and tumor progression in various tissues. OPN induces stemness by interacting with CD44, but the functional relevance of OPN-mediated interferon (IFN) signaling and hepatitis C virus (HCV) replication in stem cell populati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shirasaki, Takayoshi, Honda, Masao, Yamashita, Taro, Nio, Kouki, Shimakami, Tetsuro, Shimizu, Ryougo, Nakasyo, Saki, Murai, Kazuhisa, Shirasaki, Natsumi, Okada, Hikari, Sakai, Yoshio, Sato, Tokiharu, Suzuki, Tetsuro, Yoshioka, Katsuji, Kaneko, Shuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120883/
https://ncbi.nlm.nih.gov/pubmed/30177680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31421-6
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