2342 Protein production as an early pharmacodynamics biomarker for RNA-targeting therapies

nork Self, Wade K., Schoch, Kathleen, Bollinger, James, Cole, Tracy, Kordasiewicz, Holly, Bateman, Randall, Miller, Timothy
Argitaratua izan da J Clin Transl Sci (2018)

Protein production is an early biomarker for RNA‐targeted therapies

nork Self, Wade K., Schoch, Kathleen M., Alex, Jacob, Barthélemy, Nicolas, Bollinger, James G., Sato, Chihiro, Cole, Tracy, Kordasiewicz, Holly B., Swayze, Eric, Bateman, Randall J., Miller, Timothy M.
Argitaratua izan da Ann Clin Transl Neurol (2018)

In vivo kinetic approach reveals slow SOD1 turnover in the CNS

nork Crisp, Matthew J., Mawuenyega, Kwasi G., Patterson, Bruce W., Reddy, Naveen C., Chott, Robert, Self, Wade K., Weihl, Conrad C., Jockel-Balsarotti, Jennifer, Varadhachary, Arun S., Bucelli, Robert C., Yarasheski, Kevin E., Bateman, Randall J., Miller, Timothy M.
Argitaratua izan da J Clin Invest (2015)

Defining SOD1 ALS natural history to guide therapeutic clinical trial design

nork Bali, Taha, Self, Wade, Liu, Jingxia, Siddique, Teepu, Wang, Leo H, Bird, Thomas D, Ratti, Elena, Atassi, Nazem, Boylan, Kevin B, Glass, Jonathan D, Maragakis, Nicholas J, Caress, James B, McCluskey, Leo F, Appel, Stanley H, Wymer, James P, Gibson, Summer, Zinman, Lorne, Mozaffar, Tahseen, Callaghan, Brian, McVey, April L, Jockel-Balsarotti, Jennifer, Allred, Peggy, Fisher, Elena R, Lopate, Glenn, Pestronk, Alan, Cudkowicz, Merit E, Miller, Timothy M
Argitaratua izan da J Neurol Neurosurg Psychiatry (2016)