175. From Mechanisms to Medicines: Relations Between Inflammatory/Oxidative Pathways, Schizophrenia Symptoms, and Opportunities for Intervention

Por Sedlak, Thomas
Publicado no Schizophr Bull (2017)

Cycling the Wagons for Biliverdin Reductase

Por Sedlak, Thomas W., Snyder, Solomon H.
Publicado em 2009

DISC1 Pathway in Brain Development: Exploring Therapeutic Targets for Major Psychiatric Disorders

Por Kamiya, Atsushi, Sedlak, Thomas W., Pletnikov, Mikhail V.
Publicado em 2012

Oxidative stress and schizophrenia: recent breakthroughs from an old story

Por Emiliani, Francesco E., Sedlak, Thomas W., Sawa, Akira
Publicado em 2014

The diverse functions of GAPDH: views from different subcellular compartments

Por Tristan, Carlos, Shahani, Neelam, Sedlak, Thomas W., Sawa, Akira
Publicado em 2010

175.2 A Glu That Binds Inflammation and Neurotransmission: Glutathione as a Glutamate Reservoir

Por Sedlak, Thomas, Koga, Minori, Shaffer, Lindsay, Fahey, Jed, Snyder, Solomon, Barker, Peter, Sawa, Akira
Publicado no Schizophr Bull (2017)

Bilirubin and glutathione have complementary antioxidant and cytoprotective roles

Por Sedlak, Thomas W., Saleh, Masoumeh, Higginson, Daniel S., Paul, Bindu D., Juluri, Krishna R., Snyder, Solomon H.
Publicado em 2009

Behavioral Effects of Cocaine Mediated by Nitric Oxide-GAPDH Transcriptional Signaling

Por Xu, Risheng, Serritella, Anthony V., Sen, Tanusree, Farook, Justin M., Sedlak, Thomas W., Baraban, Jay, Snyder, Solomon H., Sen, Nilkantha
Publicado em 2013

Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness

Por Johnson, Alexander W., Jaaro-Peled, Hanna, Shahani, Neelam, Sedlak, Thomas W., Zoubovsky, Sandra, Burruss, Daniel, Emiliani, Francesco, Sawa, Akira, Gallagher, Michela
Publicado em 2013

Glutathione is a Physiologic Reservoir of Neuronal Glutamate

Por Koga, Minori, Serritella, Anthony V., Messmer, Marcus M., Hayashi-Takagi, Akiko, Hester, Lynda D., Snyder, Solomon H., Sawa, Akira, Sedlak, Thomas W.
Publicado em 2011

Constituents of Bile, Bilirubin and TUDCA, Protect Against Oxidative Stress-Induced Retinal Degeneration

Por Oveson, Brian C., Iwase, Takeshi, Hackett, Sean F., Lee, Sun Young, Usui, Shinichi, Sedlak, Thomas W., Snyder, Solomon H., Campochiaro, Peter A., Sung, Jennifer U.
Publicado em 2010

Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects: A Clinical Pilot Study

Por Sedlak, Thomas W., Nucifora, Leslie G., Koga, Minori, Shaffer, Lindsay S., Higgs, Cecilia, Tanaka, Teppei, Wang, Anna M., Coughlin, Jennifer M., Barker, Peter B., Fahey, Jed W., Sawa, Akira
Publicado no Mol Neuropsychiatry (2018)

Role of Apoptosis Signal-regulating Kinase 1 (ASK1) as an Activator of the GAPDH-Siah1 Stress-Signaling Cascade

Por Tristan, Carlos A., Ramos, Adriana, Shahani, Neelam, Emiliani, Francesco E., Nakajima, Hidemitsu, Noeh, Christopher C., Kato, Yoshinori, Takeuchi, Tadayoshi, Noguchi, Takuya, Kadowaki, Hisae, Sedlak, Thomas W., Ishizuka, Koko, Ichijo, Hidenori, Sawa, Akira
Publicado no J Biol Chem (2015)

DISC1 regulates trafficking and processing of APP and Aβ generation

Por Shahani, Neelam, Seshadri, Saurav, Jaaro-Peled, Hanna, Ishizuka, Koko, Hirota-Tsuyada, Yuki, Wang, Qi, Koga, Minori, Sedlak, Thomas W., Korth, Carsten, Brandon, Nicholas J., Kamiya, Atsushi, Subramaniam, Srinivasa, Tomoda, Toshifumi, Sawa, Akira
Publicado no Mol Psychiatry (2014)

Early postnatal GABA(A) receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1

Por Saito, Atsushi, Taniguchi, Yu, Rannals, Matthew D., Merfeld, Emily B., Ballinger, Michael D., Koga, Minori, Ohtani, Yoshikazu, Gurley, David A., Sedlak, Thomas W., Cross, Alan, Moss, Stephen J., Brandon, Nicholas J., Maher, Brady J., Kamiya, Atsushi
Publicado no Mol Psychiatry (2016)

Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy

Por Kano, Shin-ichi, Yuan, Ming, Cardarelli, Ross A., Maegawa, Gustavo, Higurashi, Norimichi, Gaval-Cruz, Meriem, Wilson, Ashley M., Tristan, Carlos, Kondo, Mari A., Chen, Yian, Koga, Minori, Obie, Cassandra, Ishizuka, Koko, Seshadri, Saurav, Srivastava, Rupali, Kato, Takahiro A., Horiuchi, Yasue, Sedlak, Thomas W., Lee, Yohan, Rapoport, Judith L., Hirose, Shinichi, Okano, Hideyuki, Valle, David, O'Donnell, Patricio, Sawa, Akira, Kai, Mihoko
Publicado no Curr Mol Med (2015)