The simplified reference tissue model: model assumption violations and their impact on binding potential

door Salinas, Cristian A, Searle, Graham E, Gunn, Roger N
Gepubliceerd in J Cereb Blood Flow Metab (2015)

Impact of image-based motion correction on dopamine D3/D2 receptor occupancy—comparison of groupwise and frame-by-frame registration approaches

door Jiao, Jieqing, Searle, Graham E., Schnabel, Julia A., Gunn, Roger N.
Gepubliceerd in EJNMMI Phys (2015)

Specificity of translocator protein-targeted positron emission tomography in inflammatory joint disease

door Helo, Yusuf, Searle, Graham E., Borghese, Federica, Abraham, Sonya, Saleem, Azeem
Gepubliceerd in EJNMMI Res (2020)

Imaging Aβ and tau in early stage Alzheimer’s disease with [(18)F]AV45 and [(18)F]AV1451

door Firouzian, Azadeh, Whittington, Alex, Searle, Graham E., Koychev, Ivan, Zamboni, Giovanna, Lovestone, Simon, Gunn, Roger N.
Gepubliceerd in EJNMMI Res (2018)

Imaging cortical dopamine D(1) receptors using [(11)C]NNC112 and ketanserin blockade of the 5-HT(2A) receptors

door Catafau, Ana M, Searle, Graham E, Bullich, Santiago, Gunn, Roger N, Rabiner, Eugenii A, Herance, Raul, Radua, Joaquim, Farre, Magi, Laruelle, Marc
Gepubliceerd in 2010

Combining PET biodistribution and equilibrium dialysis assays to assess the free brain concentration and BBB transport of CNS drugs

door Gunn, Roger N, Summerfield, Scott G, Salinas, Cristian A, Read, Kevin D, Guo, Qi, Searle, Graham E, Parker, Christine A, Jeffrey, Phil, Laruelle, Marc
Gepubliceerd in 2012

Relationship between neuromelanin and dopamine terminals within the Parkinson’s nigrostriatal system

door Martín-Bastida, Antonio, Lao-Kaim, Nicholas P, Roussakis, Andreas Antonios, Searle, Graham E, Xing, Yue, Gunn, Roger N, Schwarz, Stefan T, Barker, Roger A, Auer, Dorothee P, Piccini, Paola
Gepubliceerd in Brain (2019)

Connectivity-Based Functional Analysis of Dopamine Release in the Striatum Using Diffusion-Weighted MRI and Positron Emission Tomography

door Tziortzi, Andri C., Haber, Suzanne N., Searle, Graham E., Tsoumpas, Charalampos, Long, Christopher J., Shotbolt, Paul, Douaud, Gwenaelle, Jbabdi, Saad, Behrens, Timothy E. J., Rabiner, Eugenii A., Jenkinson, Mark, Gunn, Roger N.
Gepubliceerd in 2014

In Vivo Imaging of Cerebral Dopamine D3 Receptors in Alcoholism

door Erritzoe, David, Tziortzi, Andri, Bargiela, David, Colasanti, Alessandro, Searle, Graham E, Gunn, Roger N, Beaver, John D, Waldman, Adam, Nutt, David J, Bani, Massimo, Merlo-Pich, Emilio, Rabiner, Eugenii A, Lingford-Hughes, Anne
Gepubliceerd in 2014

Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humans

door Shotbolt, Paul, Tziortzi, Andri C, Searle, Graham E, Colasanti, Alessandro, van der Aart, Jasper, Abanades, Sergio, Plisson, Christophe, Miller, Sam R, Huiban, Mickael, Beaver, John D, Gunn, Roger N, Laruelle, Marc, Rabiner, Eugenii A
Gepubliceerd in 2012

Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer

door Saleem, Azeem, Searle, Graham E, Kenny, Laura M, Huiban, Mickael, Kozlowski, Kasia, Waldman, Adam D, Woodley, Laura, Palmieri, Carlo, Lowdell, Charles, Kaneko, Tomomi, Murphy, Philip S, Lau, Mike R, Aboagye, Eric O, Coombes, Raoul C
Gepubliceerd in EJNMMI Res (2015)

Erratum to: Lapatinib access into normal brain and brain metastases in patients with Her-2 overexpressing breast cancer

door Saleem, Azeem, Searle, Graham E., Kenny, Laura M., Huiban, Mickael, Kozlowski, Kasia, Waldman, Adam D., Woodley, Laura, Palmieri, Carlo, Lowdell, Charles, Kaneko, Tomomi, Murphy, Philip S., Lau, Mike R., Aboagye, Eric O., Coombes, Raoul C.
Gepubliceerd in EJNMMI Res (2017)

Prediction of repeat-dose occupancy from single-dose data: characterisation of the relationship between plasma pharmacokinetics and brain target occupancy

door Abanades, Sergio, van der Aart, Jasper, Barletta, Julien AR, Marzano, Carmine, Searle, Graham E, Salinas, Cristian A, Ahmad, Javaad J, Reiley, Richard R, Pampols-Maso, Sabina, Zamuner, Stefano, Cunningham, Vincent J, Rabiner, Eugenii A, Laruelle, Marc A, Gunn, Roger N
Gepubliceerd in 2011

Serotonin release measured in the human brain: a PET study with [(11)C]CIMBI-36 and d-amphetamine challenge

door Erritzoe, David, Ashok, Abhishekh H., Searle, Graham E., Colasanti, Alessandro, Turton, Samuel, Lewis, Yvonne, Huiban, Mickael, Moz, Sara, Passchier, Jan, Saleem, Azeem, Beaver, John, Lingford-Hughes, Anne, Nutt, David J., Howes, Oliver D., Gunn, Roger N., Knudsen, Gitte M., Rabiner, Eugenii A.
Gepubliceerd in Neuropsychopharmacology (2019)

Evidence for GABA‐A receptor dysregulation in gambling disorder: correlation with impulsivity

door Mick, Inge, Ramos, Anna C., Myers, Jim, Stokes, Paul R., Chandrasekera, Samantha, Erritzoe, David, Mendez, Maria A., Gunn, Roger N., Rabiner, Eugenii A., Searle, Graham E., Galduróz, José C. F., Waldman, Adam D., Bowden‐Jones, Henrietta, Clark, Luke, Nutt, David J., Lingford‐Hughes, Anne R.
Gepubliceerd in Addict Biol (2016)

Blunted Endogenous Opioid Release Following an Oral Amphetamine Challenge in Pathological Gamblers

door Mick, Inge, Myers, Jim, Ramos, Anna C, Stokes, Paul R A, Erritzoe, David, Colasanti, Alessandro, Gunn, Roger N, Rabiner, Eugenii A, Searle, Graham E, Waldman, Adam D, Parkin, Mark C, Brailsford, Alan D, Galduróz, José C F, Bowden-Jones, Henrietta, Clark, Luke, Nutt, David J, Lingford-Hughes, Anne R
Gepubliceerd in Neuropsychopharmacology (2016)

A positron emission tomography imaging study to confirm target engagement in the lungs of patients with idiopathic pulmonary fibrosis following a single dose of a novel inhaled αvβ...

door Maher, Toby M., Simpson, Juliet K., Porter, Joanna C., Wilson, Frederick J., Chan, Robert, Eames, Rhena, Cui, Yi, Siederer, Sarah, Parry, Simon, Kenny, Julia, Slack, Robert J., Sahota, Jagdeep, Paul, Lyn, Saunders, Peter, Molyneaux, Philip L., Lukey, Pauline T., Rizzo, Gaia, Searle, Graham E., Marshall, Richard P., Saleem, Azeem, Kang’ombe, Arthur R., Fairman, David, Fahy, William A., Vahdati-Bolouri, Mitra
Gepubliceerd in Respir Res (2020)