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Imaging cortical dopamine D(1) receptors using [(11)C]NNC112 and ketanserin blockade of the 5-HT(2A) receptors
[(11)C]NNC112 (8-chloro-7-hydroxy-3-methyl-5-(7-benzofuranyl)-2,3,4,5-tetrahydro-IH-3-benzazepine), a selective positron-emission tomography (PET) ligand for the D(1) receptor (R) over the 5-HT(2A) R in vitro, has shown lower selectivity in vivo, hampering measurement of D(1) R in the cortex. [(11)C...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949183/ https://ncbi.nlm.nih.gov/pubmed/20029452 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.269 |
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