Imaging cortical dopamine D(1) receptors using [(11)C]NNC112 and ketanserin blockade of the 5-HT(2A) receptors

[(11)C]NNC112 (8-chloro-7-hydroxy-3-methyl-5-(7-benzofuranyl)-2,3,4,5-tetrahydro-IH-3-benzazepine), a selective positron-emission tomography (PET) ligand for the D(1) receptor (R) over the 5-HT(2A) R in vitro, has shown lower selectivity in vivo, hampering measurement of D(1) R in the cortex. [(11)C...

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Bibliografische gegevens
Hoofdauteurs: Catafau, Ana M, Searle, Graham E, Bullich, Santiago, Gunn, Roger N, Rabiner, Eugenii A, Herance, Raul, Radua, Joaquim, Farre, Magi, Laruelle, Marc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2010
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949183/
https://ncbi.nlm.nih.gov/pubmed/20029452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2009.269
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