The X-Ray Crystal Structure of the Human Mono-Oxygenase Cytochrome P450 3A5-Ritonavir Complex Reveals Active Site Differences between P450s 3A4 and 3A5

Por Hsu, Mei-Hui, Savas, Uzen, Johnson, Eric F.
Publicado no Mol Pharmacol (2018)

Structural Characterization of the Complex between α-Naphthoflavone and Human Cytochrome P450 1B1

Por Wang, An, Savas, Uzen, Stout, C. David, Johnson, Eric F.
Publicado em 2011

Genistein, Resveratrol, and 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside Induce Cytochrome P450 4F2 Expression through an AMP-Activated Protein Kinase-Dependent Pathway

Por Hsu, Mei-Hui, Savas, Üzen, Lasker, Jerome M., Johnson, Eric F.
Publicado em 2011

Crystal Structure of Human Cytochrome P450 2D6 with Prinomastat Bound

Por Wang, An, Savas, Uzen, Hsu, Mei-Hui, Stout, C. David, Johnson, Eric F.
Publicado em 2012

20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: NORMALIZATION OF BLOOD PRESSURE BY SODIUM RESTRICTION, HYDROCHLOR...

Por Savas, Üzen, Wei, Shouzou, Hsu, Mei-Hui, Falck, John R., Guengerich, F. Peter, Capdevila, Jorge H., Johnson, Eric F.
Publicado no J Biol Chem (2016)

Opposing Roles of Peroxisome Proliferator-activated Receptor α and Growth Hormone in the Regulation of CYP4A11 Expression in a Transgenic Mouse Model

Por Savas, Üzen, Machemer, Daniel E. W., Hsu, Mei-Hui, Gaynor, Pryce, Lasker, Jerome M., Tukey, Robert H., Johnson, Eric F.
Publicado em 2009

Heme–thiolate sulfenylation of human cytochrome P450 4A11 functions as a redox switch for catalytic inhibition

Por Albertolle, Matthew E., Kim, Donghak, Nagy, Leslie D., Yun, Chul-Ho, Pozzi, Ambra, Savas, Üzen, Johnson, Eric F., Guengerich, F. Peter
Publicado no J Biol Chem (2017)

Cytochrome P450 CYP1B1 determines susceptibility to 7,12-dimethylbenz[a]anthracene-induced lymphomas

Por Buters, Jeroen T. M., Sakai, Shuichi, Richter, Thomas, Pineau, Thierry, Alexander, David L., Savas, Uzen, Doehmer, Johannes, Ward, Jerrold M., Jefcoate, Colin R., Gonzalez, Frank J.
Publicado em 1999