Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain

מאת Bigalke, Janna M., Aibara, Shintaro, Roth, Robert, Dahl, Göran, Gordon, Euan, Dorbéus, Sarah, Amunts, A., Sandmark, Jenny
הוצא לאור ב Sci Adv (2019)

Structural analysis identifies an escape route from the adverse lipogenic effects of liver X receptor ligands

מאת Belorusova, Anna Y., Evertsson, Emma, Hovdal, Daniel, Sandmark, Jenny, Bratt, Emma, Maxvall, Ingela, Schulman, Ira G., Åkerblad, Peter, Lindstedt, Eva-Lotte
הוצא לאור ב Commun Biol (2019)

Structure and biophysical characterization of the human full-length neurturin–GFRa2 complex: A role for heparan sulfate in signaling

מאת Sandmark, Jenny, Dahl, Göran, Öster, Linda, Xu, Bingze, Johansson, Patrik, Akerud, Tomas, Aagaard, Anna, Davidsson, Pia, Bigalke, Janna M., Winzell, Maria Sörhede, Rainey, G. Jonah, Roth, Robert G.
הוצא לאור ב J Biol Chem (2018)

Discovery of AZD2716: A Novel Secreted Phospholipase A(2) (sPLA(2)) Inhibitor for the Treatment of Coronary Artery Disease

מאת Giordanetto, Fabrizio, Pettersen, Daniel, Starke, Ingemar, Nordberg, Peter, Dahlström, Mikael, Knerr, Laurent, Selmi, Nidhal, Rosengren, Birgitta, Larsson, Lars-Olof, Sandmark, Jenny, Castaldo, Marie, Dekker, Niek, Karlsson, Ulla, Hurt-Camejo, Eva
הוצא לאור ב ACS Med Chem Lett (2016)

Creating Novel Activated Factor XI Inhibitors through Fragment Based Lead Generation and Structure Aided Drug Design

מאת Fjellström, Ola, Akkaya, Sibel, Beisel, Hans-Georg, Eriksson, Per-Olof, Erixon, Karl, Gustafsson, David, Jurva, Ulrik, Kang, Daiwu, Karis, David, Knecht, Wolfgang, Nerme, Viveca, Nilsson, Ingemar, Olsson, Thomas, Redzic, Alma, Roth, Robert, Sandmark, Jenny, Tigerström, Anna, Öster, Linda
הוצא לאור ב PLoS One (2015)

Design of Selective sPLA(2)-X Inhibitor (−)-2-{2-[Carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl]pyridine-2-yl}propanoic Acid

מאת Giordanetto, Fabrizio, Knerr, Laurent, Nordberg, Peter, Pettersen, Daniel, Selmi, Nidhal, Beisel, Hans-Georg, de la Motte, Hannah, Månsson, Åsa, Dahlström, Mikael, Broddefalk, Johan, Saarinen, Gabrielle, Klingegård, Fredrik, Hurt-Camejo, Eva, Rosengren, Birgitta, Wikström, Johannes, Wågberg, Maria, Brengdahl, Johan, Rohman, Mattias, Sandmark, Jenny, Åkerud, Tomas, Roth, Robert G., Jansen, Frank, Ahlqvist, Marie
הוצא לאור ב ACS Med Chem Lett (2018)

Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A(2) Type X (sPLA(2)-X) Inhibitors

מאת Knerr, Laurent, Giordanetto, Fabrizio, Nordberg, Peter, Pettersen, Daniel, Selmi, Nidhal, Beisel, Hans-Georg, de la Motte, Hannah, Olsson, Thomas, Perkins, Tim D. J., Herslöf, Margareta, Månsson, Åsa, Dahlström, Mikael, Starke, Ingemar, Broddefalk, Johan, Saarinen, Gabrielle, Klingegård, Fredrik, Hurt-Camejo, Eva, Rosengren, Birgitta, Brengdahl, Johan, Jansen, Frank, Rohman, Mattias, Sandmark, Jenny, Hallberg, Kenth, Åkerud, Tomas, Roth, Robert G., Ahlqvist, Marie
הוצא לאור ב ACS Med Chem Lett (2018)

Identification and analyses of inhibitors targeting apolipoprotein(a) kringle domains KIV-7, KIV-10, and KV provide insight into kringle domain function

מאת Sandmark, Jenny, Tigerström, Anna, Akerud, Tomas, Althage, Magnus, Antonsson, Thomas, Blaho, Stefan, Bodin, Cristian, Boström, Jonas, Chen, Yantao, Dahlén, Anders, Eriksson, Per-Olof, Evertsson, Emma, Fex, Tomas, Fjellström, Ola, Gustafsson, David, Herslöf, Margareta, Hicks, Ryan, Jarkvist, Emelie, Johansson, Carina, Kalies, Inge, Karlsson Svalstedt, Birgitta, Kartberg, Fredrik, Legnehed, Anne, Martinsson, Sofia, Moberg, Andreas, Ridderström, Marianne, Rosengren, Birgitta, Sabirsh, Alan, Thelin, Anders, Vinblad, Johanna, Wellner, Annika U., Xu, Bingze, Östlund-Lindqvist, Ann-Margret, Knecht, Wolfgang
הוצא לאור ב J Biol Chem (2020)