TAS-116, a novel Hsp90 inhibitor, selectively enhances radio-sensitivity of human cancer cells to X-rays and carbon ion radiation

Por Lee, Younghyun, Sunada, Shigeaki, Hirakawa, Hirokazu, Fujimori, Akira, Nickoloff, Jac A., Okayasu, Ryuichi
Publicado no Mol Cancer Ther (2016)

The purine scaffold Hsp90 inhibitor PU-H71 sensitizes cancer cells to heavy ion radiation by inhibiting DNA repair by homologous recombination and non-homologous end joining

Por Lee, Younghyun, Li, Huizi, Masaoka, Aya, Sunada, Shigeaki, Hirakawa, Hirokazu, Fujimori, Akira, Nickoloff, Jac A., Okayasu, Ryuichi
Publicado no Radiother Oncol (2016)

Nontoxic concentration of DNA‐PK inhibitor NU7441 radio‐sensitizes lung tumor cells with little effect on double strand break repair

Por Sunada, Shigeaki, Kanai, Hideki, Lee, Younghyun, Yasuda, Takeshi, Hirakawa, Hirokazu, Liu, Cuihua, Fujimori, Akira, Uesaka, Mitsuru, Okayasu, Ryuichi
Publicado no Cancer Sci (2016)

VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation

Por Fujisawa, Hiroshi, Nakajima, Nakako Izumi, Sunada, Shigeaki, Lee, Younghyun, Hirakawa, Hirokazu, Yajima, Hirohiko, Fujimori, Akira, Uesaka, Mitsuru, Okayasu, Ryuichi
Publicado no Radiat Oncol (2015)

Monoglucosyl-rutin as a potential radioprotector in mammalian cells

Por SUNADA, SHIGEAKI, FUJISAWA, HIROSHI, CARTWRIGHT, IAN M., MAEDA, JUNKO, BRENTS, COLLEEN A., MIZUNO, KAZUE, AIZAWA, YASUSHI, KATO, TAKAMITSU A., UESAKA, MITSURU
Publicado em 2014