Design and Synthesis of Potent Macrocyclic HIV-1 Protease Inhibitors Involving P1-P2 Ligands

von Ghosh, Arun K., Schiltz, Gary E., Rusere, Linah N., Osswald, Heather L., Walters, D. Eric, Amano, Masayuki, Mitsuya, Hiroaki
Veröffentlicht 2014

Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants

von Rusere, Linah N., Matthew, Ashley N., Lockbaum, Gordon J., Jahangir, Muhammad, Newton, Alicia, Petropoulos, Christos J., Huang, Wei, Kurt Yilmaz, Nese, Schiffer, Celia A., Ali, Akbar
Veröffentlicht in ACS Med Chem Lett (2018)

HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2′ Ligands to Optimize Hydrogen Bonding in the Substrate Envelope

von Rusere, Linah N., Lockbaum, Gordon J., Lee, Sook-Kyung, Henes, Mina, Kosovrasti, Klajdi, Spielvogel, Ean, Nalivaika, Ellen A., Swanstrom, Ronald, Yilmaz, Nese Kurt, Schiffer, Celia A., Ali, Akbar
Veröffentlicht in J Med Chem (2019)

Inhibiting HTLV-1 Protease: A Viable Antiviral Target

von Lockbaum, Gordon J., Henes, Mina, Talledge, Nathaniel, Rusere, Linah N., Kosovrasti, Klajdi, Nalivaika, Ellen A., Somasundaran, Mohan, Ali, Akbar, Mansky, Louis M., Yilmaz, Nese Kurt, Schiffer, Celia A.
Veröffentlicht in ACS Chem Biol (2021)

Structural Adaptation of Darunavir Analogs Against Primary Mutations in HIV-1 Protease

von Lockbaum, Gordon J., Leidner, Florian, Rusere, Linah N., Henes, Mina, Kosovrasti, Klajdi, Nachum, Gily S., Nalivaika, Ellen A., Bolon, Daniel N.A., Ali, Akbar, Yilmaz, Nese Kurt, Schiffer, Celia A.
Veröffentlicht in ACS Infect Dis (2018)

Correction to Structural Adaptation of Darunavir Analogues against Primary Mutations in HIV-1 Protease.

von Lockbaum, Gordon J., Leidner, Florian, Rusere, Linah N., Henes, Mina, Kosovrasti, Klajdi, Nachum, Gily S., Nalivaika, Ellen A., Bolon, Daniel N.A., Ali, Akbar, Yilmaz, Nese Kurt, Schiffer, Celia A.
Veröffentlicht in ACS Infect Dis (2019)

Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-Tetrahydrofuran in a Pseudo-Symmetric Dipeptide Isostere

von Rusere, Linah N., Lockbaum, Gordon J., Henes, Mina, Lee, Sook-Kyung, Spielvogel, Ean, Rao, Desaboini Nageswara, Kosovrasti, Klajdi, Nalivaika, Ellen A., Swanstrom, Ronald, Yilmaz, Nese Kurt, Schiffer, Celia A., Ali, Akbar
Veröffentlicht in J Med Chem (2020)

Drug design strategies to avoid resistance in direct-acting antivirals and beyond

von Matthew, Ashley N., Leidner, Florian, Lockbaum, Gordon J., Henes, Mina, Zephyr, Jacqueto, Hou, Shurong, Desaboini, Nages Rao, Timm, Jennifer, Rusere, Linah N., Ragland, Debra A., Paulsen, Janet L., Prachanronarong, Kristina, Soumana, Djade I., Nalivaika, Ellen A., Yilmaz, Nese Kurt, Ali, Akbar, Schiffer, Celia A
Veröffentlicht in Chem Rev (2021)