Protease Activated Receptor-1 Deficiency Diminishes Bleomycin-Induced Skin Fibrosis

Por Duitman, JanWillem, Ruela-de-Sousa, Roberta R, Shi, Kun, de Boer, Onno J, Borensztajn, Keren S, Florquin, Sandrine, Peppelenbosch, Maikel P, Spek, C Arnold
Publicado em 2014

Knocking Down Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP) Reverts Chemoresistance through Inactivation of Src and Bcr-Abl Proteins

Por Ferreira, Paula A., Ruela-de-Sousa, Roberta R., Queiroz, Karla C. S., Souza, Ana Carolina S., Milani, Renato, Pilli, Ronaldo Aloise, Peppelenbosch, Maikel P., den Hertog, Jeroen, Ferreira, Carmen V.
Publicado em 2012

Triggering of Protection Mechanism against Phoneutria nigriventer Spider Venom in the Brain

Por Rapôso, Catarina, Odorissi, Paulo Alexandre Miranda, Savioli, Stefania Fioravanti, Hell, Rafaela Chitarra Rodrigues, Simões, Gustavo Ferreira, Ruela-de-Sousa, Roberta R., de Oliveira, Alexandre Leite Rodrigues, da Cruz-Höfling, Maria Alice
Publicado em 2014

Violacein Induces Death of Resistant Leukaemia Cells via Kinome Reprogramming, Endoplasmic Reticulum Stress and Golgi Apparatus Collapse

Por Queiroz, Karla C. S., Milani, Renato, Ruela-de-Sousa, Roberta R., Fuhler, Gwenny M., Justo, Giselle Z., Zambuzzi, Willian F., Duran, Nelson, Diks, Sander H., Spek, C. Arnold, Ferreira, Carmen V., Peppelenbosch, Maikel P.
Publicado em 2012

Low molecular weight protein tyrosine phosphatase (LMWPTP) upregulation mediates malignant potential in colorectal cancer

Por Hoekstra, Elmer, Kodach, Liudmila L., Das, Asha M., Ruela-de-Sousa, Roberta R., Ferreira, Carmen V., Hardwick, James C., van der Woude, C. Janneke, Peppelenbosch, Maikel P., ten Hagen, Timo L.M., Fuhler, Gwenny M.
Publicado no Oncotarget (2015)

SGC-AAK1-1: A Chemical Probe Targeting AAK1 and BMP2K

Por Wells, Carrow, Couñago, Rafael M., Limas, Juanita C., Almeida, Tuanny L., Cook, Jeanette Gowen, Drewry, David H., Elkins, Jonathan M., Gileadi, Opher, Kapadia, Nirav R., Lorente-Macias, Alvaro, Pickett, Julie E., Riemen, Alexander, Ruela-de-Sousa, Roberta R., Willson, Timothy M., Zhang, Cunyu, Zuercher, William J., Zutshi, Reena, Axtman, Alison D.
Publicado no ACS Med Chem Lett (2019)

WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop

Por Agajanian, Megan J., Walker, Matthew P., Axtman, Alison D., Ruela-de-Sousa, Roberta R., Serafin, D. Stephen, Rabinowitz, Alex D., Graham, David M., Ryan, Meagan B., Tamir, Tigist, Nakamichi, Yuko, Gammons, Melissa V., Bennett, James M., Couñago, Rafael M., Drewry, David H., Elkins, Jonathan M., Gileadi, Carina, Gileadi, Opher, Godoi, Paulo H., Kapadia, Nirav, Müller, Susanne, Santiago, André S., Sorrell, Fiona J., Wells, Carrow I., Fedorov, Oleg, Willson, Timothy M., Zuercher, William J., Major, Michael B.
Publicado no Cell Rep (2019)