Knocking Down Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP) Reverts Chemoresistance through Inactivation of Src and Bcr-Abl Proteins

The development of multidrug resistance (MDR) limits the efficacy of continuous chemotherapeutic treatment in chronic myelogenous leukemia (CML). Low molecular weight protein tyrosine phosphatase (LMW-PTP) is up-regulated in several cancers and has been associated to poor prognosis. This prompted us...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ferreira, Paula A., Ruela-de-Sousa, Roberta R., Queiroz, Karla C. S., Souza, Ana Carolina S., Milani, Renato, Pilli, Ronaldo Aloise, Peppelenbosch, Maikel P., den Hertog, Jeroen, Ferreira, Carmen V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2012
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434132/
https://ncbi.nlm.nih.gov/pubmed/22957062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044312
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