Derivatives of Procaspase-Activating Compound 1 (PAC-1) and Anticancer Activities

著者: Roth, Howard S., Hergenrother, Paul J.
出版年 Curr Med Chem (2016)

N-heterocyclic carbene-catalyzed rearrangements of vinyl sulfones()

著者: Atienza, Roxanne L., Roth, Howard S., Scheidt, Karl A.
出版事項 2011

Synthesis of [5,6]-Bicyclic Heterocycles with a Ring-Junction Nitrogen via Rh(III)-Catalyzed C-H Functionalization of Alkenyl Azoles

著者: Halskov, Kim Søholm, Roth, Howard S., Ellman, Jonathan A.
出版年 Angew Chem Int Ed Engl (2017)

NHC-Catalyzed Reactions of Aryloxyacetaldehydes: A Domino Elimination/Conjugate Addition/Acylation Process for the Synthesis of Substituted Coumarins

著者: Phillips, Eric M., Wadamoto, Manabu, Roth, Howard S., Ott, Andrew W., Scheidt, Karl A.
出版事項 2009

The combination of vemurafenib and procaspase-3 activation is synergistic in mutant BRAF melanomas

著者: Peh, Jessie, Fan, Timothy M., Wycislo, Kathryn L., Roth, Howard S., Hergenrother, Paul J.
出版年 Mol Cancer Ther (2016)

Removal of Metabolic Liabilities Enables Development of Derivatives of Procaspase-Activating Compound 1 (PAC-1) with Improved Pharmacokinetics

著者: Roth, Howard S., Botham, Rachel C., Schmid, Steven C., Fan, Timothy M., Dirikolu, Levent, Hergenrother, Paul J.
出版年 J Med Chem (2015)

Small-Molecule Procaspase-3 Activation Sensitizes Cancer to Treatment with Diverse Chemotherapeutics

著者: Botham, Rachel C., Roth, Howard S., Book, Alison P., Roady, Patrick J., Fan, Timothy M., Hergenrother, Paul J.
出版年 ACS Cent Sci (2016)

Parallel Synthesis and Biological Evaluation of 837 Analogues of Procaspase-Activating Compound 1 (PAC-1)

著者: Hsu, Danny C., Roth, Howard S., West, Diana C., Botham, Rachel C., Novotny, Chris J., Schmid, Steven C., Hergenrother, Paul J.
出版事項 2011

Synergistic and targeted therapy with a procaspase-3 activator and temozolomide extends survival in glioma rodent models and is feasible for the treatment of canine malignant gliom...

著者: Joshi, Avadhut D., Botham, Rachel C., Schlein, Lisa J., Roth, Howard S., Mangraviti, Antonella, Borodovsky, Alexandra, Tyler, Betty, Joslyn, Steve, Looper, Jayme S., Podell, Michael, Fan, Timothy M., Hergenrother, Paul J., Riggins, Gregory J.
出版年 Oncotarget (2017)