Removal of Metabolic Liabilities Enables Development of Derivatives of Procaspase-Activating Compound 1 (PAC-1) with Improved Pharmacokinetics

Por Roth, Howard S., Botham, Rachel C., Schmid, Steven C., Fan, Timothy M., Dirikolu, Levent, Hergenrother, Paul J.
Publicado no J Med Chem (2015)

Parallel Synthesis and Biological Evaluation of 837 Analogues of Procaspase-Activating Compound 1 (PAC-1)

Por Hsu, Danny C., Roth, Howard S., West, Diana C., Botham, Rachel C., Novotny, Chris J., Schmid, Steven C., Hergenrother, Paul J.
Publicado em 2011