Pacemaking, arrhythmias, inotropy and hypertrophy: the many possible facets of IP(3) signalling in cardiac myocytes

by Roderick, H Llewelyn, Bootman, Martin D
Published 2007

Inositol 1,4,5-trisphosphate receptors (InsP(3)R) – “exciting” players in cardiac excitation-contraction coupling?

by Roderick, H. Llewelyn, Knollmann, Björn C.
Published 2013

Cytosolic Phosphorylation of Calnexin Controls Intracellular Ca(2+) Oscillations via an Interaction with Serca2b

by Roderick, H. Llewelyn, Lechleiter, James D., Camacho, Patricia
Published 2000

Activating calcium release through inositol 1,4,5-trisphosphate receptors without inositol 1,4,5-trisphosphate

by Bootman, Martin D., Berridge, Michael J., Roderick, H. Llewelyn
Published 2002

Calcium Signaling in Cardiac Myocytes

by Fearnley, Claire J., Roderick, H. Llewelyn, Bootman, Martin D.
Published 2011

The role of the paracrine/autocrine mediator endothelin-1 in regulation of cardiac contractility and growth

by Drawnel, Faye M, Archer, Caroline R, Roderick, H Llewelyn
Published 2013

Subcellular calcium dynamics in a whole-cell model of an atrial myocyte

by Thul, Rüdiger, Coombes, Stephen, Roderick, H. Llewelyn, Bootman, Martin D.
Published 2012

ERp57 Functions as a Subunit of Specific Complexes Formed with the ER Lectins Calreticulin and Calnexin

by Oliver, Jason D., Roderick, H. Llewelyn, Llewellyn, David H., High, Stephen
Published 1999

Endothelin-1 promotes hypertrophic remodelling of cardiac myocytes by activating sustained signalling and transcription downstream of endothelin type A receptors

by Archer, Caroline R., Robinson, Emma L., Drawnel, Faye M., Roderick, H. Llewelyn
Published in Cell Signal (2017)

Glucocorticoid-mediated Inhibition of Lck Modulates the Pattern of T Cell Receptor-induced Calcium Signals by Down-regulating Inositol 1,4,5-Trisphosphate Receptors

by Harr, Michael W., Rong, Yiping, Bootman, Martin D., Roderick, H. Llewelyn, Distelhorst, Clark W.
Published 2009

Oncogenic KRAS suppresses store-operated Ca(2+) entry and I(CRAC) through ERK pathway-dependent remodelling of STIM expression in colorectal cancer cell lines.

by Pierro, Cristina, Zhang, Xuexin, Kankeu, Cynthia, Trebak, Mohamed, Bootman, Martin D., Roderick, H. Llewelyn
Published in Cell Calcium (2018)

Assessing Cardiomyocyte Excitation-Contraction Coupling Site Detection From Live Cell Imaging Using a Structurally-Realistic Computational Model of Calcium Release

by Ladd, David, Tilūnaitė, Agnė, Roderick, H. Llewelyn, Soeller, Christian, Crampin, Edmund J., Rajagopal, Vijay
Published in Front Physiol (2019)

Exposure to GSM RF Fields Does Not Affect Calcium Homeostasis in Human Endothelial Cells, Rat Pheocromocytoma Cells or Rat Hippocampal Neurons

by O'Connor, Rodney P., Madison, Steve D., Leveque, Philippe, Roderick, H. Llewelyn, Bootman, Martin D.
Published 2010

Alzheimer's disease-associated peptide Aβ(42) mobilizes ER Ca(2+) via InsP(3)R-dependent and -independent mechanisms

by Jensen, Laura E., Bultynck, Geert, Luyten, Tomas, Amijee, Hozeefa, Bootman, Martin D., Roderick, H. Llewelyn
Published 2013

Emerging roles of inositol 1,4,5-trisphosphate signaling in cardiac myocytes

by Kockskämper, Jens, Zima, Aleksey V., Roderick, H. Llewelyn, Pieske, Burkert, Blatter, Lothar A., Bootman, Martin D.
Published 2008

Calcium Signaling in Cardiomyocyte Function

by Gilbert, Guillaume, Demydenko, Kateryna, Dries, Eef, Puertas, Rosa Doñate, Jin, Xin, Sipido, Karin, Roderick, H. Llewelyn
Published in Cold Spring Harb Perspect Biol (2020)

Genes encoding ACE2, TMPRSS2 and related proteins mediating SARS-CoV-2 viral entry are upregulated with age in human cardiomyocytes

by Robinson, Emma L., Alkass, Kanar, Bergmann, Olaf, Maguire, Janet J., Roderick, H. Llewelyn, Davenport, Anthony P.
Published in J Mol Cell Cardiol (2020)

Ca(2+) Release via IP(3) Receptors Shapes the Cardiac Ca(2+) Transient for Hypertrophic Signaling

by Hunt, Hilary, Tilūnaitė, Agnė, Bass, Greg, Soeller, Christian, Roderick, H. Llewelyn, Rajagopal, Vijay, Crampin, Edmund J.
Published in Biophys J (2020)

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

by Axe, Elizabeth L., Walker, Simon A., Manifava, Maria, Chandra, Priya, Roderick, H. Llewelyn, Habermann, Anja, Griffiths, Gareth, Ktistakis, Nicholas T.
Published 2008

Calmidazolium and arachidonate activate a calcium entry pathway that is distinct from store-operated calcium influx in HeLa cells

by Peppiatt, Claire M., Holmes, Anthony M., Seo, Jeong T., Bootman, Martin D., Collins, Tony J., McMDONALD, Fraser, Roderick, H. Llewelyn
Published 2004