Crystal Structure of Patatin-17 in Complex with Aged and Non-Aged Organophosphorus Compounds

por Wijeyesakere, Sanjeeva J., Richardson, Rudy J., Stuckey, Jeanne A.
Publicado 2014

Modeling the Tertiary Structure of the Patatin Domain of Neuropathy Target Esterase

por Wijeyesakere, Sanjeeva J., Richardson, Rudy J., Stuckey, Jeanne A.
Publicado en Protein J (2007)

Motor neuron disease due to neuropathy target esterase mutation: enzyme analysis of fibroblasts from human subjects yields insights into pathogenesis

por Hein, Nichole D., Rainier, Shirley R., Richardson, Rudy J., Fink, John K.
Publicado en Toxicol Lett (2010)

Homology models of mouse and rat estrogen receptor-α ligand-binding domain created by in silico mutagenesis of a human template: molecular docking with 17ß-estradiol, diethylstilbe...

por Gonzalez, Thomas L., Rae, James M., Colacino, Justin A., Richardson, Rudy J.
Publicado en Comput Toxicol (2018)

The effect of thrombin on a 6-hydroxydopamine model of Parkinson's disease depends on timing

por Cannon, Jason R., Hua, Ya, Richardson, Rudy J., Xi, Guohua, Keep, Richard F., Schallert, Timothy
Publicado 2007

Constructs of human neuropathy target esterase catalytic domain containing mutations related to motor neuron disease have altered enzymatic properties

por Hein, Nichole D., Stuckey, Jeanne A., Rainier, Shirley R., Fink, John K., Richardson., Rudy J.
Publicado en Toxicol Lett (2010)

Evaluation of von Willebrand Factor and von Willebrand Factor Propeptide in Models of Vascular Endothelial Cell Activation, Perturbation, and/or Injury

por Brott, David A., Katein, Anne, Thomas, Heath, Lawton, Michael, Montgomery, Robert R., Richardson, Rudy J., Louden, Calvert S.
Publicado en Toxicol Pathol (2014)

Neuropathy target esterase (NTE/PNPLA6) and organophosphorus compound-induced delayed neurotoxicity (OPIDN)()

por Richardson, Rudy J., Fink, John K., Glynn, Paul, Hufnagel, Robert B., Makhaeva, Galina F., Wijeyesakere, Sanjeeva J.
Publicado en Adv Neurotoxicol (2020)

Network Analysis of Toxic Chemicals and Symptoms: Implications for Designing First-Responder Systems

por Bhavnani, Suresh K., Abraham, Annie, Demeniuk, Christopher, Gebrekristos, Messeret, Gong, Abe, Nainwal, Satyendra, Vallabha, Gautam K., Richardson, Rudy J.
Publicado 2007

Metabolites of n-Butylparaben and iso-Butylparaben Exhibit Estrogenic Properties in MCF-7 and T47D Human Breast Cancer Cell Lines

por Gonzalez, Thomas L, Moos, Rebecca K, Gersch, Christina L, Johnson, Michael D, Richardson, Rudy J, Koch, Holger M, Rae, James M
Publicado en Toxicol Sci (2018)

Mixed Inhibition of Adenosine Deaminase Activity by 1,3-Dinitrobenzene: A Model for Understanding Cell-Selective Neurotoxicity in Chemically-Induced Energy Deprivation Syndromes in...

por Wang, Yipei, Liu, Xin, Schneider, Brandon, Zverina, Elaina A., Russ, Kristen, Wijeyesakere, Sanjeeva J., Fierke, Carol A., Richardson, Rudy J., Philbert, Martin A.
Publicado 2012

Diethyl [2,2,2-trifluoro-1-phenyl­sulfonyl­amino-1-(trifluoro­meth­yl)eth­yl]phospho­nate

por Wijeyesakere, Sanjeeva J., Nasser, Faik A., Kampf, Jeff W., Aksinenko, Alexey Y., Sokolov, Vladimir B., Malygin, Vladimir V., Makhaeva, Galina F., Richardson, Rudy J.
Publicado 2008

Further studies toward a mouse model for biochemical assessment of neuropathic potential of organophosphorus compounds

por Makhaeva, Galina F., Rudakova, Elena V., Hein, Nichole D., Serebryakova, Olga G., Kovaleva, Nadezhda V., Boltneva, Natalia P., Fink, John K., Richardson, Rudy J.
Publicado 2014

Neuropathy Target Esterase Gene Mutations Cause Motor Neuron Disease

por Rainier, Shirley, Bui, Melanie, Mark, Erin, Thomas, Donald, Tokarz, Debra, Ming, Lei, Delaney, Colin, Richardson, Rudy J., Albers, James W., Matsunami, Nori, Stevens, Jeff, Coon, Hilary, Leppert, Mark, Fink, John K.
Publicado 2008

New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer...

por Makhaeva, Galina F., Kovaleva, Nadezhda V., Boltneva, Natalia P., Lushchekina, Sofya V., Astakhova, Tatiana Yu., Rudakova, Elena V., Proshin, Alexey N., Serkov, Igor V., Radchenko, Eugene V., Palyulin, Vladimir A., Bachurin, Sergey O., Richardson, Rudy J.
Publicado en Molecules (2020)

Conjugates of methylene blue with γ-carboline derivatives as new multifunctional agents for the treatment of neurodegenerative diseases

por Bachurin, Sergey O., Makhaeva, Galina F., Shevtsova, Elena F., Boltneva, Natalia P., Kovaleva, Nadezhda V., Lushchekina, Sofya V., Rudakova, Elena V., Dubova, Ludmila G., Vinogradova, Daria V., Sokolov, Vladimir B., Aksinenko, Alexey Yu., Fisenko, Vladimir P., Richardson, Rudy J., Aliev, Gjumrakch
Publicado en Sci Rep (2019)

New Multifunctional Agents Based on Conjugates of 4-Amino-2,3-polymethylenequinoline and Butylated Hydroxytoluene for Alzheimer’s Disease Treatment

por Makhaeva, Galina F., Kovaleva, Nadezhda V., Rudakova, Elena V., Boltneva, Natalia P., Lushchekina, Sofya V., Faingold, Irina I., Poletaeva, Darya A., Soldatova, Yuliya V., Kotelnikova, Raisa A., Serkov, Igor V., Ustinov, Anatoly K., Proshin, Alexey N., Radchenko, Eugene V., Palyulin, Vladimir A., Richardson, Rudy J.
Publicado en Molecules (2020)

Neuropathy target esterase impairments cause Oliver–McFarlane and Laurence–Moon syndromes

por Hufnagel, Robert B, Arno, Gavin, Hein, Nichole D, Hersheson, Joshua, Prasad, Megana, Anderson, Yvonne, Krueger, Laura A, Gregory, Louise C, Stoetzel, Corinne, Jaworek, Thomas J, Hull, Sarah, Li, Abi, Plagnol, Vincent, Willen, Christi M, Morgan, Thomas M, Prows, Cynthia A, Hegde, Rashmi S, Riazuddin, Saima, Grabowski, Gregory A, Richardson, Rudy J, Dieterich, Klaus, Huang, Taosheng, Revesz, Tamas, Martinez-Barbera, J P, Sisk, Robert A, Jefferies, Craig, Houlden, Henry, Dattani, Mehul T, Fink, John K, Dollfus, Helene, Moore, Anthony T, Ahmed, Zubair M
Publicado en J Med Genet (2014)