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Evaluation of von Willebrand Factor and von Willebrand Factor Propeptide in Models of Vascular Endothelial Cell Activation, Perturbation, and/or Injury

Pharmacologically, vasoactive agents targeting endothelial and/or smooth muscle cells (SMC) are known to cause acute drug-induced vascular injury (DIVI) and the resulting pathology is due to endothelial cell (EC) perturbation, activation, and/or injury. Alteration in EC structure and/or function may...

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Bibliographic Details
Published in:Toxicol Pathol
Main Authors: Brott, David A., Katein, Anne, Thomas, Heath, Lawton, Michael, Montgomery, Robert R., Richardson, Rudy J., Louden, Calvert S.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222990/
https://ncbi.nlm.nih.gov/pubmed/24499802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623313518664
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