B-13 progenitor-derived hepatocytes (B-13/H cells) model lipid dysregulation in response to drugs and chemicals

by Leitch, Alistair C., Probert, Philip M.E., Shayman, James A., Meyer, Stephanie K., Kass, George E.N., Wright, Matthew C.
Published in Toxicology (2017)

Pancreatic B-13 Cell Trans-Differentiation to Hepatocytes Is Dependent on Epigenetic-Regulated Changes in Gene Expression

by Fairhall, Emma A., Charles, Michelle A., Probert, Philip M. E., Wallace, Karen, Gibb, Jennifer, Ravindan, Chandni, Soloman, Martin, Wright, Matthew C.
Published in PLoS One (2016)

Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1′-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism

by Probert, Philip M., Palmer, Jeremy M., Alhusainy, Wasma, Amer, Aimen O., Rietjens, Ivonne M.C.M., White, Steven A., Jones, David E., Wright, Matthew C.
Published in Toxicol Lett (2016)

Utility of B-13 Progenitor-Derived Hepatocytes in Hepatotoxicity and Genotoxicity Studies

by Probert, Philip M. E., Chung, Git W., Cockell, Simon J., Agius, Loranne, Mosesso, Pasquale, White, Steven A., Oakley, Fiona, Brown, Colin D. A., Wright, Matthew C.
Published 2014

Environmental Xenoestrogens Super-Activate a Variant Murine ER Beta in Cholangiocytes

by Meyer, Stephanie K., Probert, Philip M. E., Lakey, Anne K., Leitch, Alastair C., Blake, Lynsay I., Jowsey, Paul A., Cooke, Martin P., Blain, Peter G., Wright, Matthew C.
Published in Toxicol Sci (2017)

Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation

by Amer, Aimen O., Probert, Philip M., Dunn, Michael, Knight, Margaret, Vallance, Abigail E., Flecknell, Paul A., Oakley, Fiona, Cameron, Iain, White, Steven A., Blain, Peter G., Wright, Matthew C.
Published in PLoS One (2015)

Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse

by Meyer, Stephanie K., Probert, Philip M.E., Lakey, Anne F., Axon, Andrew R., Leitch, Alistair C., Williams, Faith M., Jowsey, Paul A., Blain, Peter G., Kass, George E.N., Wright, Matthew C.
Published in Toxicol Lett (2017)

The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects

by Leitch, Alistair C., Abdelghany, Tarek M., Probert, Philip M., Dunn, Michael P., Meyer, Stephanie K., Palmer, Jeremy M., Cooke, Martin P., Blake, Lynsay I., Morse, Katie, Rosenmai, Anna K., Oskarsson, Agneta, Bates, Lucy, Figueiredo, Rodrigo S., Ibrahim, Ibrahim, Wilson, Colin, Abdelkader, Noha F., Jones, David E., Blain, Peter G., Wright, Matthew C.
Published in Food Chem Toxicol (2020)

Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis

by Probert, Philip M., Leitch, Alistair C., Dunn, Michael P., Meyer, Stephanie K., Palmer, Jeremy M., Abdelghany, Tarek M., Lakey, Anne F., Cooke, Martin P., Talbot, Helen, Wills, Corinne, McFarlane, William, Blake, Lynsay I., Rosenmai, Anna K., Oskarsson, Agneta, Figueiredo, Rodrigo, Wilson, Colin, Kass, George E., Jones, David E., Blain, Peter G., Wright, Matthew C.
Published in J Hepatol (2018)