B-13 progenitor-derived hepatocytes (B-13/H cells) model lipid dysregulation in response to drugs and chemicals

par Leitch, Alistair C., Probert, Philip M.E., Shayman, James A., Meyer, Stephanie K., Kass, George E.N., Wright, Matthew C.
Publié dans Toxicology (2017)

Pancreatic B-13 Cell Trans-Differentiation to Hepatocytes Is Dependent on Epigenetic-Regulated Changes in Gene Expression

par Fairhall, Emma A., Charles, Michelle A., Probert, Philip M. E., Wallace, Karen, Gibb, Jennifer, Ravindan, Chandni, Soloman, Martin, Wright, Matthew C.
Publié dans PLoS One (2016)

Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1′-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism

par Probert, Philip M., Palmer, Jeremy M., Alhusainy, Wasma, Amer, Aimen O., Rietjens, Ivonne M.C.M., White, Steven A., Jones, David E., Wright, Matthew C.
Publié dans Toxicol Lett (2016)

Utility of B-13 Progenitor-Derived Hepatocytes in Hepatotoxicity and Genotoxicity Studies

par Probert, Philip M. E., Chung, Git W., Cockell, Simon J., Agius, Loranne, Mosesso, Pasquale, White, Steven A., Oakley, Fiona, Brown, Colin D. A., Wright, Matthew C.
Publié 2014

Environmental Xenoestrogens Super-Activate a Variant Murine ER Beta in Cholangiocytes

par Meyer, Stephanie K., Probert, Philip M. E., Lakey, Anne K., Leitch, Alastair C., Blake, Lynsay I., Jowsey, Paul A., Cooke, Martin P., Blain, Peter G., Wright, Matthew C.
Publié dans Toxicol Sci (2017)

Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation

par Amer, Aimen O., Probert, Philip M., Dunn, Michael, Knight, Margaret, Vallance, Abigail E., Flecknell, Paul A., Oakley, Fiona, Cameron, Iain, White, Steven A., Blain, Peter G., Wright, Matthew C.
Publié dans PLoS One (2015)

Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse

par Meyer, Stephanie K., Probert, Philip M.E., Lakey, Anne F., Axon, Andrew R., Leitch, Alistair C., Williams, Faith M., Jowsey, Paul A., Blain, Peter G., Kass, George E.N., Wright, Matthew C.
Publié dans Toxicol Lett (2017)

The toxicity of the methylimidazolium ionic liquids, with a focus on M8OI and hepatic effects

par Leitch, Alistair C., Abdelghany, Tarek M., Probert, Philip M., Dunn, Michael P., Meyer, Stephanie K., Palmer, Jeremy M., Cooke, Martin P., Blake, Lynsay I., Morse, Katie, Rosenmai, Anna K., Oskarsson, Agneta, Bates, Lucy, Figueiredo, Rodrigo S., Ibrahim, Ibrahim, Wilson, Colin, Abdelkader, Noha F., Jones, David E., Blain, Peter G., Wright, Matthew C.
Publié dans Food Chem Toxicol (2020)

Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis

par Probert, Philip M., Leitch, Alistair C., Dunn, Michael P., Meyer, Stephanie K., Palmer, Jeremy M., Abdelghany, Tarek M., Lakey, Anne F., Cooke, Martin P., Talbot, Helen, Wills, Corinne, McFarlane, William, Blake, Lynsay I., Rosenmai, Anna K., Oskarsson, Agneta, Figueiredo, Rodrigo, Wilson, Colin, Kass, George E., Jones, David E., Blain, Peter G., Wright, Matthew C.
Publié dans J Hepatol (2018)