Gene Array and Fluorescence In situ Hybridization Biomarkers of Activity of Saracatinib (AZD0530), a Src Inhibitor, in a Preclinical Model of Colorectal Cancer

Por Arcaroli, John J., Touban, Basel M., Tan, Aik Choon, Varella-Garcia, Marileila, Powell, Rebecca W., Eckhardt, S. Gail, Elvin, Paul, Gao, Dexiang, Messersmith, Wells A.
Publicado em 2010

ALDH+ tumor‐initiating cells exhibiting gain in NOTCH1 gene copy number have enhanced regrowth sensitivity to a γ‐secretase inhibitor and irinotecan in colorectal cancer

Por Arcaroli, John J., Powell, Rebecca W., Varella-Garcia, Marileila, McManus, Martine, Tan, Aik Choon, Quackenbush, Kevin S., Pitts, Todd M., Gao, Dexiang, Spreafico, Anna, Dasari, Arvind, Touban, Basel M., Messersmith, Wells A.
Publicado em 2012

Common PIK3CA Mutants and a Novel 3′ UTR Mutation Are Associated with Increased Sensitivity to Saracatinib

Por Arcaroli, John J., Quackenbush, Kevin S., Powell, Rebecca W., Pitts, Todd M., Spreafico, Anna, Varella-Garcia, Marileila, Bemis, Lynne, Tan, Aik Choon, Reinemann, Jaclyn M., Touban, Basel M., Dasari, Arvind, Eckhardt, S. Gail, Messersmith, Wells A.
Publicado em 2012