New Era for Novel CNS Drug Development

Por Potter, William Z
Publicado em 2012

Mining the secrets of the CSF: developing biomarkers of neurodegeneration

Por Potter, William Z.
Publicado em 2012

Optimizing Early “Go/No Go” Decisions in CNS Drug Development

Por Potter, William Z
Publicado no Expert Rev Clin Pharmacol (2014)

Proteomic Biomarkers for Brain Disorders: Technical Considerations and Challenges

Por Brady, Linda S, Potter, William Z
Publicado em 2014

Redirecting the revolution: New developments in drug development for psychiatry

Por Brady, Linda S., Potter, William Z., Gordon, Joshua A.
Publicado no Expert Opin Drug Discov (2019)

Conceptual, Regulatory and Strategic Imperatives in the Early Days of EEG-Based Biomarker Validation for Neurodevelopmental Disabilities

Por Ewen, Joshua B., Sweeney, John A., Potter, William Z.
Publicado no Front Integr Neurosci (2019)

De-risking Psychiatric Drug Development: The NIMH’s Fast Fail Program, a Novel Precompetitive Model

Por Grabb, Margaret C., Cross, Alan J., Potter, William Z., McCracken, James T.
Publicado no J Clin Psychopharmacol (2016)

Soluble BACE-1 Activity and sAβPPβ Concentrations in Alzheimer’s Disease and Age-Matched Healthy Control Cerebrospinal Fluid from the Alzheimer’s Disease Neuroimaging Initiative-1...

Por Savage, Mary J., Holder, Daniel J., Wu, Guoxin, Kaplow, June, Siuciak, Judith A., Potter, William Z.
Publicado no J Alzheimers Dis (2015)

Translational and Early Phase Strategies for Treatment Development: Report of ISCTM Autumn 2013 Symposium

Por Young, Jared W., Potter, William Z., Riley, Steve, Groeneveld, Geert J., Kinon, Bruce J., Egan, Mike F., Feltner, Douglas E.
Publicado no Innov Clin Neurosci (2015)

A Randomized, Placebo-Controlled, Crossover Pilot Trial of the Oral Selective NR2B Antagonist MK-0657 in Patients With Treatment-Resistant Major Depressive Disorder

Por Ibrahim, Lobna, DiazGranados, Nancy, Jolkovsky, Libby, Brutsche, Nancy, Luckenbaugh, David A., Herring, W. Joseph, Potter, William Z., Zarate, Carlos A.
Publicado em 2012

Imaging as a biomarker in drug discovery for Alzheimer’s disease: is MRI a suitable technology?

Por Merlo Pich, Emilio, Jeromin, Andreas, Frisoni, Giovanni B, Hill, Derek, Lockhart, Andrew, Schmidt, Mark E, Turner, Martin R, Mondello, Stefania, Potter, William Z
Publicado no Alzheimers Res Ther (2014)

Translating Glutamate: From Pathophysiology to Treatment

Por Javitt, Daniel C., Schoepp, Darryle, Kalivas, Peter W., Volkow, Nora D., Zarate, Carlos, Merchant, Kalpana, Bear, Mark F., Umbricht, Daniel, Hajos, Mihaly, Potter, William Z., Lee, Chi-Ming
Publicado em 2011

Revolutionizing Alzheimer's disease and clinical trials through biomarkers

Por Mattsson, Niklas, Carrillo, Maria C., Dean, Robert A., Devous, Michael D., Nikolcheva, Tania, Pesini, Pedro, Salter, Hugh, Potter, William Z., Sperling, Reisa S., Bateman, Randall J., Bain, Lisa J., Liu, Enchi
Publicado no Alzheimers Dement (Amst) (2015)

Development and Evaluation of a Multiplexed Mass Spectrometry-Based Assay for Measuring Candidate Peptide Biomarkers in Alzheimer’s Disease Neuroimaging Initiative (ADNI) CSF

Por Spellman, Daniel S., Wildsmith, Kristin R., Honigberg, Lee A., Tuefferd, Marianne, Baker, David, Raghavan, Nandini, Nairn, Angus C., Croteau, Pascal, Schirm, Michael, Allard, Rene, Lamontagne, Julie, Chelsky, Daniel, Hoffmann, Steven, Potter, William Z.
Publicado no Proteomics Clin Appl (2015)

Selective kappa-opioid antagonism ameliorates anhedonic behavior: evidence from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS)

Por Pizzagalli, Diego A., Smoski, Moria, Ang, Yuen-Siang, Whitton, Alexis E., Sanacora, Gerard, Mathew, Sanjay J., Nurnberger, John, Lisanby, Sarah H., Iosifescu, Dan V., Murrough, James W., Yang, Hongqiu, Weiner, Richard D., Calabrese, Joseph R., Goodman, Wayne, Potter, William Z., Krystal, Andrew D.
Publicado no Neuropsychopharmacology (2020)

Biomarkers Associated With the Apolipoprotein E Genotype and Alzheimer Disease

Por Soares, Holly D., Potter, William Z., Pickering, Eve, Kuhn, Max, Immermann, Frederick W., Shera, David M, Ferm, Mats, Dean, Robert A., Simon, Adam J., Swenson, Frank, Siuciak, Judith A., Kaplow, June, Thambisetty, Madhav, Zagouras, Panayiotis, Koroshetz, Walter J., Wan, Hong I., Trojanowski, John Q., Shaw, Leslie M.
Publicado em 2012

A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms

Por Fleming, Leah M., Javitt, Daniel C., Carter, Cameron S., Kantrowitz, Joshua T., Girgis, Ragy R., Kegeles, Lawrence S., Ragland, John D., Maddock, Richard J., Lesh, Tyler A., Tanase, Costin, Robinson, James, Potter, William Z., Carlson, Marlene, Wall, Melanie M., Choo, Tse-Hwei, Grinband, Jack, Lieberman, Jeffrey, Krystal, John H., Corlett, Philip R.
Publicado no Neuroimage Clin (2019)

Update on the Biomarker Core of the Alzheimer's Disease Neuroimaging Initiative Subjects

Por Trojanowski, John Q, Trojanowski, John Q, Vandeerstichele, Hugo, Korecka, Magdalena, Clark, Christopher M, Aisen, Paul S, Petersen, Ronald C, Blennow, Kaj, Soares, Holly, Simon, Adam, Lewczuk, Piotr, Dean, Robert, Siemers, Eric, Potter, William Z, Weiner, Michael W, Jack, Clifford R, Jagust, William, Toga, Arthur W, Lee, Virginia M.-Y., Shaw, Leslie M
Publicado em 2010

Utility of Imaging-Based Biomarkers for Glutamate-Targeted Drug Development in Psychotic Disorders: A Randomized Clinical Trial

Por Javitt, Daniel C., Carter, Cameron S., Krystal, John H., Kantrowitz, Joshua T., Girgis, Ragy R., Kegeles, Lawrence S., Ragland, John D., Maddock, Richard J., Lesh, Tyler A., Tanase, Costin, Corlett, Philip R., Rothman, Douglas L., Mason, Graeme, Qiu, Maolin, Robinson, James, Potter, William Z., Carlson, Marlene, Wall, Melanie M., Choo, Tse-Hwei, Grinband, Jack, Lieberman, Jeffrey A.
Publicado no JAMA Psychiatry (2017)

High Resolution Discovery Proteomics Reveals Candidate Disease Progression Markers of Alzheimer’s Disease in Human Cerebrospinal Fluid

Por Hendrickson, Ronald C., Lee, Anita Y. H., Song, Qinghua, Liaw, Andy, Wiener, Matt, Paweletz, Cloud P., Seeburger, Jeffrey L., Li, Jenny, Meng, Fanyu, Deyanova, Ekaterina G., Mazur, Matthew T., Settlage, Robert E., Zhao, Xuemei, Southwick, Katie, Du, Yi, Holder, Dan, Sachs, Jeffrey R., Laterza, Omar F., Dallob, Aimee, Chappell, Derek L., Snyder, Karen, Modur, Vijay, King, Elizabeth, Joachim, Catharine, Bondarenko, Andrey Y., Shearman, Mark, Soper, Keith A., Smith, A. David, Potter, William Z., Koblan, Ken S., Sachs, Alan B., Yates, Nathan A.
Publicado no PLoS One (2015)