Activation of receptor tyrosine kinases mediates acquired resistance to MEK inhibition in malignant peripheral nerve sheath tumors

Autor Wang, Jiawan, Pollard, Kai, Calizo, Ana, Pratilas, Christine A.
Vydáno v Cancer Res (2020)

Combined inhibition of SHP2 and MEK is effective in models of NF1-deficient malignant peripheral nerve sheath tumors

Autor Wang, Jiawan, Pollard, Kai, Allen, Amy N., Tomar, Tushar, Pijnenburg, Dirk, Yao, Zhan, Rodriguez, Fausto J., Pratilas, Christine A.
Vydáno v Cancer Res (2020)

Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling

Autor Grit, Jamie L., Johnson, Benjamin K., Dischinger, Patrick S., J. Essenburg, Curt, Adams, Marie, Campbell, Stacy, Pollard, Kai, Pratilas, Christine A., Triche, Tim J., Graveel, Carrie R., Steensma, Matthew R.
Vydáno v Epigenetics Chromatin (2021)

A clinically and genomically annotated nerve sheath tumor biospecimen repository

Autor Pollard, Kai, Banerjee, Jineta, Doan, Xengie, Wang, Jiawan, Guo, Xindi, Allaway, Robert, Langmead, Shannon, Slobogean, Bronwyn, Meyer, Christian F., Loeb, David M., Morris, Carol D., Belzberg, Allan J., Blakeley, Jaishri O., Rodriguez, Fausto J., Guinney, Justin, Gosline, Sara J. C., Pratilas, Christine A.
Vydáno v Sci Data (2020)

Chromosome 8 gain is associated with high-grade transformation in MPNST

Autor Dehner, Carina, Moon, Chang In, Zhang, Xiyuan, Zhou, Zhaohe, Miller, Chris, Xu, Hua, Wan, Xiaodan, Yang, Kuangying, Mashl, Jay, Gosline, Sara J.C., Wang, Yuxi, Zhang, Xiaochun, Godec, Abigail, Jones, Paul A., Dahiya, Sonika, Bhatia, Himanshi, Primeau, Tina, Li, Shunqiang, Pollard, Kai, Rodriguez, Fausto J., Ding, Li, Pratilas, Christine A., Shern, Jack F., Hirbe, Angela C.
Vydáno v JCI Insight (2021)