Annulation of Thioimidates and Vinyl Carbodiimides to Prepare 2-Aminopyrimidines, Competent Nucleophiles for Intramolecular Alkyne Hydroamination. Synthesis of (−)-Crambidine

由 Perl, Nicholas R., Ide, Nathan D., Prajapati, Sudeep, Perfect, Hahdi H., Durón, Sergio G., Gin, David Y.
出版 2010

Design and Synthesis of Potent Quillaja Saponin Vaccine Adjuvants

由 Adams, Michelle M., Damani, Payal, Perl, Nicholas R., Won, Annie, Hong, Feng, Livingston, Philip O., Ragupathi, Govind, Gin, David Y.
出版 2010

The Soluble Guanylate Cyclase Stimulator IWP-953 Increases Conventional Outflow Facility in Mouse Eyes

由 Ge, Pei, Navarro, Iris D., Kessler, Marco M., Bernier, Sylvie G., Perl, Nicholas R., Sarno, Renee, Masferrer, Jaime, Hannig, Gerhard, Stamer, W. Daniel
發表在 Invest Ophthalmol Vis Sci (2016)

Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans

由 Nakai, Takashi, Perl, Nicholas R., Barden, Timothy C., Carvalho, Andrew, Fretzen, Angelika, Germano, Peter, Im, G-Yoon J., Jin, Hong, Kim, Charles, Lee, Thomas W.-H., Long, Kimberly, Moore, Joel, Rohde, Jason M., Sarno, Renee, Segal, Chrissie, Solberg, Erik O., Tobin, Jenny, Zimmer, Daniel P., Currie, Mark G.
發表在 ACS Med Chem Lett (2016)

Discovery of IWP-051, a novel orally bioavailable soluble guanylate cyclase stimulator with sustained and dose-dependent hemodynamic effects

由 Nakai, Takashi, Perl, Nicholas R, Iyengar, Rajesh R, Mermerian, Ara, Im, G-Yoon J, Lee, Thomas W-H, Rennie, Glen R, Jia, James, Renhowe, Paul A, Barden, Timothy C, Sheppeck, James E, Iyer, Karthik, Jung, Joon, Milne, G Todd, Segal, Chrissie, Long, Kimberly, Miyashiro, Joy, Bernier, Sylvie, Jacobson, Sarah, Tobin, Jenny, Shea, Courtney, Germano, Peter, Chien, Yueh-tyng, Zimmer, Daniel
發表在 BMC Pharmacol Toxicol (2015)