Annulation of Thioimidates and Vinyl Carbodiimides to Prepare 2-Aminopyrimidines, Competent Nucleophiles for Intramolecular Alkyne Hydroamination. Synthesis of (−)-Crambidine

بواسطة Perl, Nicholas R., Ide, Nathan D., Prajapati, Sudeep, Perfect, Hahdi H., Durón, Sergio G., Gin, David Y.
منشور في 2010

Design and Synthesis of Potent Quillaja Saponin Vaccine Adjuvants

بواسطة Adams, Michelle M., Damani, Payal, Perl, Nicholas R., Won, Annie, Hong, Feng, Livingston, Philip O., Ragupathi, Govind, Gin, David Y.
منشور في 2010

The Soluble Guanylate Cyclase Stimulator IWP-953 Increases Conventional Outflow Facility in Mouse Eyes

بواسطة Ge, Pei, Navarro, Iris D., Kessler, Marco M., Bernier, Sylvie G., Perl, Nicholas R., Sarno, Renee, Masferrer, Jaime, Hannig, Gerhard, Stamer, W. Daniel
الحاوية / القاعدة Invest Ophthalmol Vis Sci (2016)

Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans

بواسطة Nakai, Takashi, Perl, Nicholas R., Barden, Timothy C., Carvalho, Andrew, Fretzen, Angelika, Germano, Peter, Im, G-Yoon J., Jin, Hong, Kim, Charles, Lee, Thomas W.-H., Long, Kimberly, Moore, Joel, Rohde, Jason M., Sarno, Renee, Segal, Chrissie, Solberg, Erik O., Tobin, Jenny, Zimmer, Daniel P., Currie, Mark G.
الحاوية / القاعدة ACS Med Chem Lett (2016)

Discovery of IWP-051, a novel orally bioavailable soluble guanylate cyclase stimulator with sustained and dose-dependent hemodynamic effects

بواسطة Nakai, Takashi, Perl, Nicholas R, Iyengar, Rajesh R, Mermerian, Ara, Im, G-Yoon J, Lee, Thomas W-H, Rennie, Glen R, Jia, James, Renhowe, Paul A, Barden, Timothy C, Sheppeck, James E, Iyer, Karthik, Jung, Joon, Milne, G Todd, Segal, Chrissie, Long, Kimberly, Miyashiro, Joy, Bernier, Sylvie, Jacobson, Sarah, Tobin, Jenny, Shea, Courtney, Germano, Peter, Chien, Yueh-tyng, Zimmer, Daniel
الحاوية / القاعدة BMC Pharmacol Toxicol (2015)