Focus on α4β2* and α6β2* nAChRs for Parkinson’s Disease Therapeutics

Por Pérez, Xiomara A., Quik, Maryka
Publicado em 2011

Nicotine as a potential neuroprotective agent for Parkinson’s disease

Por Quik, Maryka, Perez, Xiomara A., Bordia, Tanuja
Publicado em 2012

Role of alpha6 nicotinic receptors in CNS dopaminergic function; relevance to addiction and neurological disorders

Por Quik, Maryka, Perez, Xiomara A., Grady, Sharon R.
Publicado em 2011

Long-term nicotine treatment downregulates α6β* nicotinic receptor expression and function in nucleus accumbens

Por Perez, Xiomara A., McIntosh, J. Michael, Quik, Maryka
Publicado em 2013

Role for the nicotinic cholinergic system in movement disorders; therapeutic implications

Por Quik, Maryka, Zhang, Danhui, Perez, Xiomara A., Bordia, Tanuja
Publicado em 2014

Striatal cholinergic interneurons and D2 receptor-expressing GABAergic medium spiny neurons regulate tardive dyskinesia

Por Bordia, Tanuja, Zhang, Danhui, Perez, Xiomara A., Quik, Maryka
Publicado no Exp Neurol (2016)

Striatal D1 medium spiny neuron activation induces dyskinesias in parkinsonian mice

Por Perez, Xiomara A., Zhang, Danhui, Bordia, Tanuja, Quik, Maryka
Publicado no Mov Disord (2017)

α6β2* and α4β2* Nicotinic Receptors Both Regulate Dopamine Signaling with Increased Nigrostriatal Damage: Relevance to Parkinson's Disease

Por Perez, Xiomara A., Bordia, Tanuja, McIntosh, J. Michael, Quik, Maryka
Publicado em 2010

Long-Term Nicotine Exposure Depresses Dopamine Release in Nonhuman Primate Nucleus Accumbens

Por Perez, Xiomara A., Ly, Jason, McIntosh, J. Michael, Quik, Maryka
Publicado em 2012

Optogenetic activation of striatal cholinergic interneurons regulates L-dopa-induced dyskinesias

Por Bordia, Tanuja, Perez, Xiomara A., Heiss, Jaime, Zhang, Danhui, Quik, Maryka
Publicado no Neurobiol Dis (2016)

Varenicline enhances dopamine release facilitation more than nicotine after long-term nicotine treatment and withdrawal

Por Perez, Xiomara A, Khroyan, Taline V, McIntosh, J Michael, Quik, Maryka
Publicado no Pharmacol Res Perspect (2015)

Pre-synaptic dopaminergic compensation after moderate nigrostriatal damage in non-human primates

Por Perez, Xiomara A., Parameswaran, Neeraja, Huang, Luping Z., O’Leary, Kathryn T., Quik, Maryka
Publicado em 2008

Prominent Role of α3/α6β2(*) nAChRs in Regulating Evoked Dopamine Release in Primate Putamen: Effect of Long-Term Nicotine Treatment

Por Perez, Xiomara A., O'Leary, Kathryn T., Parameswaran, Neeraja, McIntosh, J. Michael, Quik, Maryka
Publicado em 2009

Multiple roles for nicotine in Parkinson’s disease

Por Quik, Maryka, Huang, Luping Z., Parameswaran, Neeraja, Bordia, Tanuja, Campos, Carla, Perez, Xiomara A.
Publicado em 2009

Chronic nicotine treatment differentially regulates striatal α6α4β2* and α6(nonα4)β2* nAChR expression and function

Por Perez, Xiomara A., Bordia, Tanuja, McIntosh, J. Michael, Grady, Sharon R., Quik, Maryka
Publicado em 2008

Cortical nNOS neurons co-express the NK1 receptor and are depolarized by Substance P in multiple mammalian species

Por Dittrich, Lars, Heiss, Jaime E., Warrier, Deepti R., Perez, Xiomara A., Quik, Maryka, Kilduff, Thomas S.
Publicado em 2012

Nicotine-mediated improvement in L-dopa-induced dyskinesias in MPTP-lesioned monkeys is dependent on dopamine nerve terminal function

Por Quik, Maryka, Mallela, Archana, Chin, Matthew, McIntosh, J. Michael, Perez, Xiomara A., Bordia, Tanuja
Publicado em 2012

α7 nicotinic receptor agonists reduce levodopa-induced dyskinesias with severe nigrostriatal damage

Por Zhang, Danhui, McGregor, Matthew, Bordia, Tanuja, Perez, Xiomara A., McIntosh, J. Michael, Decker, Michael W., Quik, Maryka
Publicado no Mov Disord (2015)