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Pre-synaptic dopaminergic compensation after moderate nigrostriatal damage in non-human primates
Despite a dramatic loss of nigrostriatal dopaminergic neurons in Parkinson’s disease, clinical symptoms only arise with 70–80% reduction of striatal dopamine. The mechanisms responsible for this functional compensation are currently under debate. Although initial studies showed an enhanced pre-synap...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3264543/ https://ncbi.nlm.nih.gov/pubmed/18248617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05268.x |
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