New Strategies in Neuroblastoma: Therapeutic Targeting of MYCN and ALK

Por Barone, Giuseppe, Anderson, John, Pearson, Andrew D. J., Petrie, Kevin, Chesler, Louis
Publicado em 2013

p53 Cellular Localization and Function in Neuroblastoma : Evidence for Defective G(1) Arrest Despite WAF1 Induction in MYCN-Amplified Cells

Por Tweddle, Deborah A., Malcolm, Archie J., Cole, Michael, Pearson, Andrew D.J., Lunec, John
Publicado em 2001

Novel pharmacodynamic biomarkers for MYCN protein and PI3K/AKT/mTOR pathway signaling in children with neuroblastoma

Por Smith, Jennifer R., Moreno, Lucas, Heaton, Simon P., Chesler, Louis, Pearson, Andrew D.J., Garrett, Michelle D.
Publicado no Mol Oncol (2015)

Outcome and Toxicity of an Ifosfamide-Based Soft Tissue Sarcoma Treatment Protocol in Children. The Importance of Local Therapy

Por Yule, S. Murray, Skinner, Roderick, English, Martin W., Cole, Mike, Pearson, Andrew D. J., Lucraft, Helen H., Craft, Alan W.
Publicado em 1998

Intrinsic Susceptibility MRI Identifies Tumors with ALK(F1174L) Mutation in Genetically-Engineered Murine Models of High-Risk Neuroblastoma

Por Jamin, Yann, Glass, Laura, Hallsworth, Albert, George, Rani, Koh, Dow-Mu, Pearson, Andrew D. J., Chesler, Louis, Robinson, Simon P.
Publicado em 2014

Significance of MYCN Amplification in International Neuroblastoma Staging System Stage 1 and 2 Neuroblastoma: A Report From the International Neuroblastoma Risk Group Database

Por Bagatell, Rochelle, Beck-Popovic, Maja, London, Wendy B., Zhang, Yang, Pearson, Andrew D.J., Matthay, Katherine K., Monclair, Tom, Ambros, Peter F., Cohn, Susan L.
Publicado em 2009

Adaptive dosing approaches to the individualization of 13-cis-retinoic acid (isotretinoin) treatment for children with high-risk neuroblastoma

Por Veal, Gareth J., Errington, Julie, Rowbotham, Sophie E., Illingworth, Nicola A., Malik, Ghada, Cole, Michael, Daly, Ann K., Pearson, Andrew D.J., Boddy, Alan V.
Publicado em 2012

Clinical and Biologic Features Predictive of Survival After Relapse of Neuroblastoma: A Report From the International Neuroblastoma Risk Group Project

Por London, Wendy B., Castel, Victoria, Monclair, Tom, Ambros, Peter F., Pearson, Andrew D.J., Cohn, Susan L., Berthold, Frank, Nakagawara, Akira, Ladenstein, Ruth L., Iehara, Tomoko, Matthay, Katherine K.
Publicado em 2011

In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells

Por Al-Saffar, Nada M. S., Agliano, Alice, Marshall, Lynley V., Jackson, L. Elizabeth, Balarajah, Geetha, Sidhu, Jasmin, Clarke, Paul A., Jones, Chris, Workman, Paul, Pearson, Andrew D. J., Leach, Martin O.
Publicado no PLoS One (2017)

Lactate and Choline Metabolites Detected In Vitro by Nuclear Magnetic Resonance Spectroscopy Are Potential Metabolic Biomarkers for PI3K Inhibition in Pediatric Glioblastoma

Por Al-Saffar, Nada M. S., Marshall, Lynley V., Jackson, L. Elizabeth, Balarajah, Geetha, Eykyn, Thomas R., Agliano, Alice, Clarke, Paul A., Jones, Chris, Workman, Paul, Pearson, Andrew D. J., Leach, Martin O.
Publicado em 2014

A phase 1 study of oral ridaforolimus in pediatric patients with advanced solid tumors

Por Pearson, Andrew D.J., Federico, Sara M., Aerts, Isabelle, Hargrave, Darren R., DuBois, Steven G., Iannone, Robert, Geschwindt, Ryan D., Wang, Ruixue, Haluska, Frank G., Trippett, Tanya M., Geoerger, Birgit
Publicado no Oncotarget (2016)

Clinical, Biologic, and Prognostic Differences on the Basis of Primary Tumor Site in Neuroblastoma: A Report From the International Neuroblastoma Risk Group Project

Por Vo, Kieuhoa T., Matthay, Katherine K., Neuhaus, John, London, Wendy B., Hero, Barbara, Ambros, Peter F., Nakagawara, Akira, Miniati, Doug, Wheeler, Kate, Pearson, Andrew D.J., Cohn, Susan L., DuBois, Steven G.
Publicado em 2014

MGMT-INDEPENDENT TEMOZOLOMIDE RESISTANCE IN PAEDIATRIC GLIOBLASTOMA CELLS ASSOCIATED WITH A PI3-KINASE-MEDIATED HOX / STEM CELL GENE SIGNATURE

Por Gaspar, Nathalie, Marshall, Lynley, Perryman, Lara, Bax, Dorine A., Little, Suzanne E., Viana-Pereira, Marta, Sharp, Swee Y., Vassal, Gilles, Pearson, Andrew D.J., Reis, Rui M., Hargrave, Darren, Workman, Paul, Jones, Chris
Publicado em 2010

Prognostic Value of the Stage 4S Metastatic Pattern and Tumor Biology in Patients With Metastatic Neuroblastoma Diagnosed Between Birth and 18 Months of Age

Por Taggart, Denah R., London, Wendy B., Schmidt, Mary Lou, DuBois, Steven G., Monclair, Tom F., Nakagawara, Akira, De Bernardi, Bruno, Ambros, Peter F., Pearson, Andrew D.J., Cohn, Susan L., Matthay, Katherine K.
Publicado em 2011

Individualized (131)I-mIBG therapy in the management of refractory and relapsed neuroblastoma

Por George, Sally L., Falzone, Nadia, Chittenden, Sarah, Kirk, Stephanie J., Lancaster, Donna, Vaidya, Sucheta J., Mandeville, Henry, Saran, Frank, Pearson, Andrew D.J., Du, Yong, Meller, Simon T., Denis-Bacelar, Ana M., Flux, Glenn D.
Publicado no Nucl Med Commun (2016)

Metastatic Neuroblastoma Confined to Distant Lymph Nodes (stage 4N) Predicts Outcome in Patients With Stage 4 Disease: A Study From the International Neuroblastoma Risk Group Datab...

Por Morgenstern, Daniel A., London, Wendy B., Stephens, Derek, Volchenboum, Samuel L., Hero, Barbara, Di Cataldo, Andrea, Nakagawara, Akira, Shimada, Hiroyuki, Ambros, Peter F., Matthay, Katherine K., Cohn, Susan L., Pearson, Andrew D.J., Irwin, Meredith S.
Publicado no J Clin Oncol (2014)

Demonstration of the reproducibility of free-breathing diffusion-weighted MRI and dynamic contrast enhanced MRI in children with solid tumours: a pilot study

Por Miyazaki, Keiko, Jerome, Neil P., Collins, David J., Orton, Matthew R., d’Arcy, James A., Wallace, Toni, Moreno, Lucas, Pearson, Andrew D. J., Marshall, Lynley V., Carceller, Fernando, Leach, Martin O., Zacharoulis, Stergios, Koh, Dow-Mu
Publicado no Eur Radiol (2015)

Repeatability of derived parameters from histograms following non-Gaussian diffusion modelling of diffusion-weighted imaging in a paediatric oncological cohort

Por Jerome, Neil P., Miyazaki, Keiko, Collins, David J., Orton, Matthew R., d’Arcy, James A., Wallace, Toni, Moreno, Lucas, Pearson, Andrew D. J., Marshall, Lynley V., Carceller, Fernando, Leach, Martin O., Zacharoulis, Stergios, Koh, Dow-Mu
Publicado no Eur Radiol (2016)

The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report

Por Cohn, Susan L., Pearson, Andrew D.J., London, Wendy B., Monclair, Tom, Ambros, Peter F., Brodeur, Garrett M., Faldum, Andreas, Hero, Barbara, Iehara, Tomoko, Machin, David, Mosseri, Veronique, Simon, Thorsten, Garaventa, Alberto, Castel, Victoria, Matthay, Katherine K.
Publicado em 2009

Evaluation of Clinically Translatable Magnetic Resonance Imaging Biomarkers of Therapeutic Response in the TH-MYCN Transgenic Mouse Model of Neuroblastoma

Por Jamin, Yann, Tucker, Elizabeth R., Poon, Evon S., Popov, Sergey, Vaughan, Lynsey, Boult, Jessica K.R., Webber, Hannah, Hallsworth, Albert, Baker, Lauren C.J., Jones, Chris, Koh, Dow-Mu, Pearson, Andrew D.J., Chesler, Louis, Robinson, Simon P.
Publicado no Radiology (2012)