Computational Approaches to Identify Genetic Interactions for Cancer Therapeutics

Por Benstead-Hume, Graeme, Wooller, Sarah K., Pearl, Frances M.G.
Publicado no J Integr Bioinform (2017)

Identification and analysis of mutational hotspots in oncogenes and tumour suppressors

Por Baeissa, Hanadi, Benstead-Hume, Graeme, Richardson, Christopher J., Pearl, Frances M.G
Publicado no Oncotarget (2017)

CATHEDRAL: A Fast and Effective Algorithm to Predict Folds and Domain Boundaries from Multidomain Protein Structures

Por Redfern, Oliver C, Harrison, Andrew, Dallman, Tim, Pearl, Frances M. G, Orengo, Christine A
Publicado em 2007

MoKCa database—mutations of kinases in cancer

Por Richardson, Christopher J., Gao, Qiong, Mitsopoulous, Costas, Zvelebil, Marketa, Pearl, Laurence H., Pearl, Frances M. G.
Publicado em 2009

VIDA: a virus database system for the organization of animal virus genome open reading frames

Por Albà, M. Mar, Lee, David, Pearl, Frances M. G., Shepherd, Adrian J., Martin, Nigel, Orengo, Christine A., Kellam, Paul
Publicado em 2001

The CATH extended protein-family database: Providing structural annotations for genome sequences

Por Pearl, Frances M.G., Lee, David, Bray, James E., Buchan, Daniel W.A., Shepherd, Adrian J., Orengo, Christine A.
Publicado em 2002

Assigning genomic sequences to CATH

Por Pearl, Frances M. G., Lee, David, Bray, James E., Sillitoe, Ian, Todd, Annabel E., Harrison, Andrew P., Thornton, Janet M., Orengo, Christine A.
Publicado em 2000

Gene3D: Structural Assignment for Whole Genes and Genomes Using the CATH Domain Structure Database

Por Buchan, Daniel W.A., Shepherd, Adrian J., Lee, David, Pearl, Frances M.G., Rison, Stuart C.G., Thornton, Janet M., Orengo, Christine A.
Publicado em 2002

A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct

Por Ocasio, Cory A., Rajasekaran, Mohan B., Walker, Sarah, Le Grand, Darren, Spencer, John, Pearl, Frances M.G., Ward, Simon E., Savic, Velibor, Pearl, Laurence H., Hochegger, Helfrid, Oliver, Antony W.
Publicado no Oncotarget (2016)

A rapid classification protocol for the CATH Domain Database to support structural genomics

Por Pearl, Frances M. G., Martin, Nigel, Bray, James E., Buchan, Daniel W. A., Harrison, Andrew P., Lee, David, Reeves, Gabrielle A., Shepherd, Adrian J., Sillitoe, Ian, Todd, Annabel E., Thornton, Janet M., Orengo, Christine A.
Publicado em 2001

Mouse and Human Genetic Analyses Associate Kalirin with Ventral Striatal Activation during Impulsivity and with Alcohol Misuse

Por Peña-Oliver, Yolanda, Carvalho, Fabiana M., Sanchez-Roige, Sandra, Quinlan, Erin B., Jia, Tianye, Walker-Tilley, Tom, Rulten, Stuart L., Pearl, Frances M. G., Banaschewski, Tobias, Barker, Gareth J., Bokde, Arun L. W., Büchel, Christian, Conrod, Patricia J., Flor, Herta, Gallinat, Jürgen, Garavan, Hugh, Heinz, Andreas, Gowland, Penny, Paillere Martinot, Marie-Laure, Paus, Tomáš, Rietschel, Marcella, Robbins, Trevor W., Smolka, Michael N., Schumann, Gunter, Stephens, David N.
Publicado no Front Genet (2016)