Early-life stress links 5-hydroxymethylcytosine to anxiety-related behaviors

Por Papale, Ligia A., Madrid, Andy, Li, Sisi, Alisch, Reid S.
Publicado no Epigenetics (2017)

Scn8a voltage-gated sodium channel mutation alters seizure and anxiety responses to acute stress

Por Sawyer, Nikki T, Papale, Ligia A, Eliason, Jessica, Neigh, Gretchen N, Escayg, Andrew
Publicado em 2013

Genome-wide disruption of 5-hydroxymethylcytosine in a mouse model of autism

Por Papale, Ligia A., Zhang, Qi, Li, Sisi, Chen, Kailei, Keleş, Sündüz, Alisch, Reid S.
Publicado no Hum Mol Genet (2015)

Differentially Methylated Genes in Saliva are linked to Childhood Stress

Por Papale, Ligia A., Seltzer, Leslie J., Madrid, Andy, Pollak, Seth D., Alisch, Reid S.
Publicado no Sci Rep (2018)

Dysfunction of the Scn8a Voltage-gated Sodium Channel Alters Sleep Architecture, Reduces Diurnal Corticosterone Levels, and Enhances Spatial Memory

Por Papale, Ligia A., Paul, Ketema N., Sawyer, Nikki T., Manns, Joseph R., Tufik, Sergio, Escayg, Andrew
Publicado em 2010

Early-life febrile seizures worsen adult phenotypes in Scn1a mutants

Por Dutton, Stacey B. B., Dutt, Karoni, Papale, Ligia A., Helmers, Sandra, Goldin, Alan L., Escayg, Andrew
Publicado no Exp Neurol (2017)

Progesterone reduces erectile dysfunction in sleep-deprived spontaneously hypertensive rats

Por Andersen, Monica L, Martins, Raquel CS, Alvarenga, Tathiana AF, Antunes, Isabela B, Papale, Ligia A, Tufik, Sergio
Publicado em 2007

Preferential inactivation of Scn1a in parvalbumin interneurons increases seizure susceptibility

Por Dutton, Stacey B., Makinson, Christopher D., Papale, Ligia A., Shankar, Anupama, Balakrishnan, Bindu, Nakazawa, Kazu, Escayg, Andrew
Publicado em 2012

Effects of an epilepsy-causing mutation in the SCN1A sodium channel gene on cocaine-induced seizure susceptibility in mice

Por Purcell, Ryan H., Papale, Ligia A., Makinson, Christopher D., Sawyer, Nikki T., Schroeder, Jason P., Escayg, Andrew, Weinshenker, David
Publicado em 2013

Hippocampal increase of 5-hmC in the glucocorticoid receptor gene following acute stress

Por Li, Sisi, Papale, Ligia A., Kintner, Douglas B., Sabat, Grzegorz, Barrett-Wilt, Gregory A., Cengiz, Pelin, Alisch, Reid S.
Publicado no Behav Brain Res (2015)

Altered Sleep Regulation in a Mouse Model of SCN1A-Derived Genetic Epilepsy with Febrile Seizures Plus (GEFS+)

Por Papale, Ligia A., Makinson, Christopher D., Ehlen, J. Christopher, Tufik, Sergio, Decker, Michael J., Paul, Ketema N., Escayg, Andrew
Publicado em 2013

Genome-wide alterations in hippocampal 5-hydroxymethylcytosine links plasticity genes to acute stress

Por Li, Sisi, Papale, Ligia A., Zhang, Qi, Madrid, Andy, Chen, Li, Chopra, Pankaj, Keleş, Sündüz, Jin, Peng, Alisch, Reid S.
Publicado no Neurobiol Dis (2015)

Sex-specific hippocampal 5-hydroxymethylcytosine is disrupted in response to acute stress

Por Papale, Ligia A., Li, Sisi, Madrid, Andy, Zhang, Qi, Chen, Li, Chopra, Pankaj, Jin, Peng, Keleş, Sündüz, Alisch, Reid S.
Publicado no Neurobiol Dis (2016)

Glyoxalase 1 and its substrate methylglyoxal are novel regulators of seizure susceptibility

Por Distler, Margaret G., Gorfinkle, Naomi, Papale, Ligia A., Wuenschell, Gerald E., Termini, John, Escayg, Andrew, Winawer, Melodie R., Palmer, Abraham A.
Publicado em 2013

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior

Por Makinson, Christopher D., Dutt, Karoni, Lin, Frank, Papale, Ligia A., Shankar, Anupama, Barela, Arthur J., Liu, Robert, Goldin, Alan L., Escayg, Andrew
Publicado no Exp Neurol (2015)

Heterozygous mutations of the voltage-gated sodium channel SCN8A are associated with spike-wave discharges and absence epilepsy in mice

Por Papale, Ligia A., Beyer, Barbara, Jones, Julie M., Sharkey, Lisa M., Tufik, Sergio, Epstein, Michael, Letts, Verity A., Meisler, Miriam H., Frankel, Wayne N., Escayg, Andrew
Publicado em 2009

Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice

Por Chopra, Pankaj, Papale, Ligia A, White, Andrew T J, Hatch, Andrea, Brown, Ryan M, Garthwaite, Mark A, Roseboom, Patrick H, Golos, Thaddeus G, Warren, Stephen T, Alisch, Reid S
Publicado em 2014

Altered Function of the SCN1A Voltage-gated Sodium Channel Leads to γ-Aminobutyric Acid-ergic (GABAergic) Interneuron Abnormalities

Por Martin, Melinda S., Dutt, Karoni, Papale, Ligia A., Dubé, Céline M., Dutton, Stacey B., de Haan, Georgius, Shankar, Anupama, Tufik, Sergio, Meisler, Miriam H., Baram, Tallie Z., Goldin, Alan L., Escayg, Andrew
Publicado em 2010