XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases

Por Owyang, Alexander M, Issafras, Hassan, Corbin, John, Ahluwalia, Kiran, Larsen, Paul, Pongo, Elizabeth, Handa, Masahisa, Horwitz, Arnold H, Roell, Marina K, Haak-Frendscho, Mary, Masat, Linda
Publicado em 2011

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract

Por Owyang, Alexander M., Zaph, Colby, Wilson, Emma H., Guild, Katherine J., McClanahan, Terrill, Miller, Hugh R. P., Cua, Daniel J., Goldschmidt, Michael, Hunter, Christopher A., Kastelein, Robert A., Artis, David
Publicado em 2006

IL-25 regulates Th17 function in autoimmune inflammation

Por Kleinschek, Melanie A., Owyang, Alexander M., Joyce-Shaikh, Barbara, Langrish, Claire L., Chen, Yi, Gorman, Daniel M., Blumenschein, Wendy M., McClanahan, Terrill, Brombacher, Frank, Hurst, Stephen D., Kastelein, Robert A., Cua, Daniel J.
Publicado em 2007

Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice

Por Haarberg, Kelley M. K., Li, Jun, Heinrichs, Jessica, Wang, Dapeng, Liu, Chen, Bronk, Crystina C., Kaosaard, Kane, Owyang, Alexander M., Holland, Sacha, Masuda, Esteban, Tso, Kin, Blazar, Bruce R., Anasetti, Claudio, Beg, Amer A., Yu, Xue-Zhong
Publicado em 2013

Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1β Activity

Por Roell, Marina K., Issafras, Hassan, Bauer, Robert J., Michelson, Kristen S., Mendoza, Nerissa, Vanegas, Sandra I., Gross, Lisa M., Larsen, Paul D., Bedinger, Daniel H., Bohmann, David J., Nonet, Genevieve H., Liu, Naichi, Lee, Steve R., Handa, Masahisa, Kantak, Seema S., Horwitz, Arnold H., Hunter, John J., Owyang, Alexander M., Mirza, Amer M., Corbin, John A., White, Mark L.
Publicado em 2010

AMPK Activation through Mitochondrial Regulation Results in Increased Substrate Oxidation and Improved Metabolic Parameters in Models of Diabetes

Por Jenkins, Yonchu, Sun, Tian-Qiang, Markovtsov, Vadim, Foretz, Marc, Li, Wei, Nguyen, Henry, Li, Yingwu, Pan, Alison, Uy, Gerald, Gross, Lisa, Baltgalvis, Kristen, Yung, Stephanie L., Gururaja, Tarikere, Kinoshita, Taisei, Owyang, Alexander, Smith, Ira J., McCaughey, Kelly, White, Kathy, Godinez, Guillermo, Alcantara, Raniel, Choy, Carmen, Ren, Hong, Basile, Rachel, Sweeny, David J., Xu, Xiang, Issakani, Sarkiz D., Carroll, David C., Goff, Dane A., Shaw, Simon J., Singh, Rajinder, Boros, Laszlo G., Laplante, Marc-André, Marcotte, Bruno, Kohen, Rita, Viollet, Benoit, Marette, André, Payan, Donald G., Kinsella, Todd M., Hitoshi, Yasumichi
Publicado em 2013