A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region

Por Schroeder, Courtney M, Ostrem, Jonathan ML, Hertz, Nicholas T, Vale, Ronald D
Publicado no eLife (2014)

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions

Por Ostrem, Jonathan M., Peters, Ulf, Sos, Martin L., Wells, James A., Shokat, Kevan M.
Publicado no Nature (2013)

OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin

Por Chen, Ligong, Shu, Yan, Liang, Xiaomin, Chen, Eugene C., Yee, Sook Wah, Zur, Arik A., Li, Shuanglian, Xu, Lu, Keshari, Kayvan R., Lin, Michael J., Chien, Huan-Chieh, Zhang, Youcai, Morrissey, Kari M., Liu, Jason, Ostrem, Jonathan, Younger, Noah S., Kurhanewicz, John, Shokat, Kevan M., Ashrafi, Kaveh, Giacomini, Kathleen M.
Publicado em 2014