Structure of glycerol dehydrogenase from Serratia

nork Musille, Paul, Ortlund, Eric
Argitaratua 2014

Expression, purification and crystallization of the ancestral androgen receptor–DHT complex

nork Colucci, Jennifer K., Ortlund, Eric A.
Argitaratua 2013

X-Ray Crystal Structure of the Ancestral 3-Ketosteroid Receptor–Progesterone–Mifepristone Complex Shows Mifepristone Bound at the Coactivator Binding Interface

nork Colucci, Jennifer K., Ortlund, Eric A.
Argitaratua 2013

The structure, function and evolution of proteins that bind DNA and RNA

nork Hudson, William H., Ortlund, Eric A.
Argitaratua izan da Nat Rev Mol Cell Biol (2014)

Glucocorticoid Receptor Condensates Link DNA-Dependent Receptor Dimerization and Transcriptional Transactivation

nork Frank, Filipp, Liu, Xu, Ortlund, Eric
Argitaratua izan da J Endocr Soc (2021)

First High-Resolution Crystal Structures of the Glucocorticoid Receptor Ligand-Binding Domain–Peroxisome Proliferator-Activated γ Coactivator 1-α Complex with Endogenous and Synthe...

nork Liu, Xu, Wang, Yashuo, Ortlund, Eric A.
Argitaratua izan da Mol Pharmacol (2019)

SAT-LB124 Phosphatidylcholine Transfer Protein Interacts With PPARδ to Modulate Activity

nork Druzak, Samuel Adam, Mays, Suzanne, Ortlund, Eric
Argitaratua izan da J Endocr Soc (2020)

Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation

nork Frank, Filipp, Liu, Xu, Ortlund, Eric A.
Argitaratua izan da Proc Natl Acad Sci U S A (2021)

Deciphering Modern Glucocorticoid Cross-pharmacology Using Ancestral Corticosteroid Receptors

nork Kohn, Jeffrey A., Deshpande, Kirti, Ortlund, Eric A.
Argitaratua 2012

The structural basis of direct glucocorticoid-mediated transrepression

nork Hudson, William H., Youn, Christine, Ortlund, Eric A.
Argitaratua 2012

Crystal Structure of the Mineralocorticoid Receptor DNA Binding Domain in Complex with DNA

nork Hudson, William H., Youn, Christine, Ortlund, Eric A.
Argitaratua 2014

The first crystal structure of a DNA-free nuclear receptor DNA binding domain sheds light on DNA-driven allostery in the glucocorticoid receptor

nork Frank, Filipp, Okafor, C. Denise, Ortlund, Eric A.
Argitaratua izan da Sci Rep (2018)

An epistatic ratchet constrains the direction of glucocorticoid receptor evolution

nork Bridgham, Jamie T., Ortlund, Eric A., Thornton, Joseph W.
Argitaratua izan da Nature (2009)

The nuclear receptor superfamily: A structural perspective

nork Weikum, Emily R., Liu, Xu, Ortlund, Eric A.
Argitaratua izan da Protein Sci (2018)

Mechanisms for the Evolution of a Derived Function in the Ancestral Glucocorticoid Receptor

nork Carroll, Sean Michael, Ortlund, Eric A., Thornton, Joseph W.
Argitaratua 2011

Phospholipid – Driven gene regulation

nork Musille, Paul M., Kohn, Jeffrey A., Ortlund, Eric A.
Argitaratua 2013

Vestigialization of an Allosteric Switch: Genetic and Structural Mechanisms for the Evolution of Constitutive Activity in a Steroid Hormone Receptor

nork Bridgham, Jamie T., Keay, June, Ortlund, Eric A., Thornton, Joseph W.
Argitaratua 2014

Crystal structure of an ancient protein: evolution by conformational epistasis

nork Ortlund, Eric A., Bridgham, Jamie T., Redinbo, Matthew R., Thornton, Joseph W.
Argitaratua 2007

Development of Hybrid Phospholipid Mimics as Effective Agonists for Liver Receptor Homologue-1

nork Flynn, Autumn R., Mays, Suzanne G., Ortlund, Eric A., Jui, Nathan T.
Argitaratua izan da ACS Med Chem Lett (2018)

Glucocorticoid receptor control of transcription: precision and plasticity via allostery

nork Weikum, Emily R., Knuesel, Matthew T., Ortlund, Eric A., Yamamoto, Keith R.
Argitaratua izan da Nat Rev Mol Cell Biol (2017)