What does not kill you makes you stronger: surviving anti-cancer therapies by cytoskeletal remodeling and Myosin II reactivation

par Orgaz, Jose L, Sanz-Moreno, Victoria
Publié dans Mol Cell Oncol (2020)

Rho GTPases modulate malignant transformation of tumor cells

par Orgaz, Jose L, Herraiz, Cecilia, Sanz-Moreno, Victoria
Publié 2014

Modes of invasion during tumour dissemination

par Pandya, Pahini, Orgaz, Jose L., Sanz‐Moreno, Victoria
Publié dans Mol Oncol (2016)

Actomyosin contractility and collective migration: may the force be with you

par Pandya, Pahini, Orgaz, Jose L, Sanz-Moreno, Victoria
Publié dans Curr Opin Cell Biol (2017)

Pigment Epithelium-Derived Factor Blocks Tumor Extravasation by Suppressing Amoeboid Morphology and Mesenchymal Proteolysis

par Ladhani, Omar, Sánchez-Martinez, Cristina, Orgaz, Jose L, Jimenez, Benilde, Volpert, Olga V
Publié 2011

Changes in the gene expression profile of A375 human melanoma cells induced by over-expression of multifunctional pigment epithelium-derived factor

par Orgaz, Jose L., Benguria, Alberto, Sanchez-Martinez, Cristina, Ladhani, Omar, Volpert, Olga V., Jimenez, Benilde
Publié 2011

CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion

par Farrugia, Aaron J., Rodríguez, Javier, Orgaz, Jose L., Lucas, María, Sanz-Moreno, Victoria, Calvo, Fernando
Publié dans J Cell Biol (2020)

Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance Between DNA Damage and Tumor Dissemination

par Herraiz, Cecilia, Calvo, Fernando, Pandya, Pahini, Cantelli, Gaia, Rodriguez-Hernandez, Irene, Orgaz, Jose L., Kang, NaRa, Chu, Tinghine, Sahai, Erik, Sanz-Moreno, Victoria
Publié dans J Natl Cancer Inst (2015)

TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination

par Cantelli, Gaia, Orgaz, Jose L., Rodriguez-Hernandez, Irene, Karagiannis, Panagiotis, Maiques, Oscar, Matias-Guiu, Xavier, Nestle, Frank O., Marti, Rosa M., Karagiannis, Sophia N., Sanz-Moreno, Victoria
Publié dans Curr Biol (2015)

Diverse matrix metalloproteinase functions regulate cancer amoeboid migration

par Orgaz, Jose L., Pandya, Pahini, Dalmeida, Rimple, Karagiannis, Panagiotis, Sanchez-Laorden, Berta, Viros, Amaya, Albrengues, Jean, Nestle, Frank O., Ridley, Anne J., Gaggioli, Cedric, Marais, Richard, Karagiannis, Sophia N., Sanz-Moreno, Victoria
Publié 2014

Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance

par Orgaz, Jose L., Crosas-Molist, Eva, Sadok, Amine, Perdrix-Rosell, Anna, Maiques, Oscar, Rodriguez-Hernandez, Irene, Monger, Jo, Mele, Silvia, Georgouli, Mirella, Bridgeman, Victoria, Karagiannis, Panagiotis, Lee, Rebecca, Pandya, Pahini, Boehme, Lena, Wallberg, Fredrik, Tape, Chris, Karagiannis, Sophia N., Malanchi, Ilaria, Sanz-Moreno, Victoria
Publié dans Cancer Cell (2020)

WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion

par Rodriguez-Hernandez, Irene, Maiques, Oscar, Kohlhammer, Leonie, Cantelli, Gaia, Perdrix-Rosell, Anna, Monger, Joanne, Fanshawe, Bruce, Bridgeman, Victoria L., Karagiannis, Sophia N., Penin, Rosa M., Marcolval, Joaquim, Marti, Rosa M., Matias-Guiu, Xavier, Fruhwirth, Gilbert O., Orgaz, Jose L., Malanchi, Ilaria, Sanz-Moreno, Victoria
Publié dans Nat Commun (2020)

Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment

par Georgouli, Mirella, Herraiz, Cecilia, Crosas-Molist, Eva, Fanshawe, Bruce, Maiques, Oscar, Perdrix, Anna, Pandya, Pahini, Rodriguez-Hernandez, Irene, Ilieva, Kristina M., Cantelli, Gaia, Karagiannis, Panagiotis, Mele, Silvia, Lam, Hoyin, Josephs, Debra H., Matias-Guiu, Xavier, Marti, Rosa M., Nestle, Frank O., Orgaz, Jose L., Malanchi, Ilaria, Fruhwirth, Gilbert O., Karagiannis, Sophia N., Sanz-Moreno, Victoria
Publié dans Cell (2019)

Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer

par Aguilera, Óscar, González-Sancho, José Manuel, Zazo, Sandra, Rincón, Raúl, Fernández, Agustín F., Tapia, Olga, Canals, Francesc, Morte, Beatriz, Calvanese, Vincenzo, Orgaz, José L., Niell, Núria, Aguilar, Susana, Freije, José M., Graña, Osvaldo, Pisano, David G., Borrero, Aurea, Martínez-Useros, Javier, Jiménez, Benilde, Fraga, Mario F., García-Foncillas, Jesús, López-Otín, Carlos, Lafarga, Miguel, Rojo, Federico, Muñoz, Alberto
Publié dans Oncotarget (2015)